Anti-Tetanus Toxin 抗体 (ab53829)
Key features and details
- Rabbit polyclonal to Tetanus Toxin
- Suitable for: WB, ELISA
- Isotype: IgG
製品の概要
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製品名
Anti-Tetanus Toxin antibody
Tetanus Toxin 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Tetanus Toxin -
由来種
Rabbit -
アプリケーション
適用あり: WB, ELISAmore details -
種交差性
交差種: Clostridium tetani -
免疫原
Tissue, cells or virus corresponding to Tetanus Toxin. Tetanus toxoid (formaldehyde inactivated tetanus toxin).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.098% Sodium azide
Constituent: Whole serum -
Concentration information loading...
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精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab53829の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use at an assay dependent dilution. Predicted molecular weight: 150 kDa.
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ELISA |
Use at an assay dependent dilution.
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特記事項 |
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WB
Use at an assay dependent dilution. Predicted molecular weight: 150 kDa. |
ELISA
Use at an assay dependent dilution. |
ターゲット情報
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関連性
Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation. -
細胞内局在
Secreted -
別名
- Tentoxylysin antibody
- Tetanus toxin chain H antibody
- Tetanus toxin chain L antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab53829 は 2 報の論文で使用されています。
- Chai P et al. The recombinant protein combined vaccine based on the fragment C of tetanus toxin and the cross-reacting material 197. Appl Microbiol Biotechnol 105:1683-1692 (2021). PubMed: 33511443
- Mittal AM et al. Multiple network properties overcome random connectivity to enable stereotypic sensory responses. Nat Commun 11:1023 (2020). PubMed: 32094345