製品の概要

  • 製品名Terfenadine
  • 製品の詳細
    K+ channel blocker. H1 antagonist.
  • 生理活性の詳細K+ channel blocker (Kv11.1). Blocks ATP-sensitive K+ channels (IC50 = 1.2 μM). H1 receptor antagonist.
  • 精製度> 98%

製品の特性

    アプリケーション

    Our Abpromise guarantee covers the use of ab120270 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    アプリケーション Abreviews 特記事項
    Functional Studies Use at an assay dependent concentration.

    Terfenadine 画像

    • ab2893 staining γH2A.X in MALME-3M cells treated with terfenadine (ab120270), by ICC/IF. Increase of γH2A.X nuclear expression correlates with increased concentration of terfenadine, as described in literature.
      The cells were incubated at 37°C for 6 hours in media containing different concentrations of ab120270 (terfenadine) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab2893 (10 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.

    Terfenadine (ab120270) 使用論文

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