製品の概要

  • 製品名Anti-TEP1 antibody
    TEP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TEP1
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Human TEP1 (N terminal). 20 amino acid from near the N-terminus of Human TEP1.

  • ポジティブ・コントロール
    • Human skin tissue. Human breast tissue.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab64189 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 290 kDa.
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 関連性Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes. Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TEP1). Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death. High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression levels of TEP1 do not correlate with malignancy. At least two isoforms of TP1 are known to exist.
  • 細胞内局在Nuclear (probable). Telomere.
  • 参照データベース
  • 別名
    • p240 antibody
    • p80 telomerase homolog antibody
    • Telomerase associated protein 1 antibody
    • Telomerase protein component 1 antibody
    • TLP1 antibody
    • TP1 antibody
    • TROVE domain family, member 1 antibody
    • TROVE1 antibody
    • VAULT2 antibody
    see all

Anti-TEP1 antibody 画像

  • ab64189 (5ug/ml) staining TEP1 in human skin tissue by immunohistochemistry using formalin-fixed, paraffin-embedded tissue.
  • ab64189 (5ug/ml) staining TEP1 in human breast tissue by immunohistochemistry using formalin-fixed, paraffin embedded tissue.

Anti-TEP1 antibody (ab64189) 使用論文

ab64189 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"