製品の概要

  • 製品名Anti-Tenascin C antibody [DB7]
    Tenascin C 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [DB7] to Tenascin C
  • 特異性ab86182 reacts with the fibrinogen like knob domain of Tenascin C.
  • アプリケーション適用あり: IP, WB, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Tenascin polypeptides from spent culture supernatant of human fibroblasts isolated by affinity chromatography.

  • 特記事項


    ab86182 is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab86182 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at an assay dependent concentration.
WB 1/1000. Predicted molecular weight: 241 kDa.
IHC-P Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.

ターゲット情報

  • 機能Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
  • 配列類似性Belongs to the tenascin family.
    Contains 15 EGF-like domains.
    Contains 1 fibrinogen C-terminal domain.
    Contains 15 fibronectin type-III domains.
  • 細胞内局在Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 150 225 antibody
    • Cytotactin antibody
    • Glioma associated extracellular matrix antigen antibody
    • Glioma-associated-extracellular matrix antigen antibody
    • GMEM antibody
    • GP 150 225 antibody
    • GP 150-225 antibody
    • GP antibody
    • Hexabrachion antibody
    • HXB antibody
    • JI antibody
    • MGC167029 antibody
    • Miotendinous antigen antibody
    • Myotendinous antigen antibody
    • Neuronectin antibody
    • TENA_HUMAN antibody
    • Tenascin antibody
    • Tenascin-C antibody
    • Tenascin-C isoform 14/AD1/16 antibody
    • TenascinC antibody
    • TN antibody
    • TN C antibody
    • TN-C antibody
    • TNC antibody
    see all

Anti-Tenascin C antibody [DB7] 画像

  • Immunohistochemical analysis of Human cornea tissue, staining Tenascin C wih ab86182.

    Tissue was taken from healthy patients (left) or patients with granular dystrophy (right). Sections were blocked with blocking solution for 30 minutes at room temperature before incubation with primary antibody (1/50) overnight at 4°C. Staining was detected with DAB.

Anti-Tenascin C antibody [DB7] (ab86182) 使用論文

This product has been referenced in:
  • Szalai E  et al. Fibrillin-2, tenascin-C, matrilin-2, and matrilin-4 are strongly expressed in the epithelium of human granular and lattice type I corneal dystrophies. Mol Vis 18:1927-36 (2012). IHC-P ; Human . Read more (PubMed: 22876117) »
  • Tiitta O  et al. Enhanced tenascin expression in cervical and vulvar koilocytotic lesions. Am J Pathol 141:907-13 (1992). Read more (PubMed: 1384340) »

See all 2 Publications for this product

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