製品の概要

  • 製品名Anti-TECPR1 antibody
    TECPR1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TECPR1
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Human TECPR1.

  • ポジティブ・コントロール
    • A375 cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • 特記事項(精製)Purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab92384 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 130 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
    • 配列類似性Belongs to the TECPR1 family.
      Contains 1 PH domain.
      Contains 9 TECPR repeats.
    • ドメインThe PH domain mediates the binding to phosphatidylinositol-3-phosphate (PtdIns(3)P). While full-length protein is unable to bind PtdIns(3)P in vitro, it is assumed that the binding to the ATG5-ATG12 conjugate exposes the PH domain, allowing the association with PtdIns(3)P (PubMed:22342342).
    • 細胞内局在Cytoplasmic vesicle > autophagosome membrane. Lysosome membrane. Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes.
    • Information by UniProt
    • 参照データベース
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    Anti-TECPR1 antibody 画像

    • Anti-TECPR1 antibody (ab92384) at 1/100 dilution + A375 cell lysate at 35 µg

      Predicted band size : 130 kDa

    Anti-TECPR1 antibody (ab92384) 使用論文

    ab92384 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab92384.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"