製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to TECPR1
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Human TECPR1.

  • ポジティブ・コントロール
    • A375 cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Protein A purified
  • 特記事項(精製)
    Purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab92384 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報
    ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 130 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
    • 配列類似性
      Belongs to the TECPR1 family.
      Contains 1 PH domain.
      Contains 9 TECPR repeats.
    • ドメイン
      The PH domain mediates the binding to phosphatidylinositol-3-phosphate (PtdIns(3)P). While full-length protein is unable to bind PtdIns(3)P in vitro, it is assumed that the binding to the ATG5-ATG12 conjugate exposes the PH domain, allowing the association with PtdIns(3)P (PubMed:22342342).
    • 細胞内局在
      Cytoplasmic vesicle > autophagosome membrane. Lysosome membrane. Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 2210010N04Rik antibody
      • DKFZP434B0335 antibody
      • FLJ23419 antibody
      • FLJ90593 antibody
      • KIAA1358 antibody
      • MGC124730 antibody
      • mKIAA1358 antibody
      • RGD1306873 antibody
      • TCPR1_HUMAN antibody
      • Tecpr1 antibody
      • tectonin beta propeller repeat containing 1 antibody
      • Tectonin beta-propeller repeat-containing protein 1 antibody
      see all

    Anti-TECPR1 antibody 画像

    • Anti-TECPR1 antibody (ab92384) at 1/100 dilution + A375 cell lysate at 35 µg

      Predicted band size : 130 kDa

    プロトコール

    Anti-TECPR1 antibody (ab92384) 使用論文

    ab92384 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab92384.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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