製品の概要
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製品名Anti-TdT antibody [41A]
TdT 一次抗体 製品一覧 -
製品の詳細Mouse monoclonal [41A] to TdT
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由来種Mouse
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アプリケーション適用あり: IHC-P, ELISA, WBmore details
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種交差性交差種: Human
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免疫原
Recombinant full length protein
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ポジティブ･コントロール
- Thymus.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーPreservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS -
Concentration information loading... -
精製度IgG fraction
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特記事項（精製）This antibody was purified using a AKTA prime.
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ポリ/モノモノクローナル
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クローン名41A
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アイソタイプIgG2a
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab68886 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P | 1/100. | |
| ELISA | 1/1000. | |
| WB | 1/100. Detects a band of approximately 60 kDa (predicted molecular weight: 58 kDa). |
ターゲット情報
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機能Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
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配列類似性Belongs to the DNA polymerase type-X family.
Contains 1 BRCT domain. -
細胞内局在Nucleus.
- Information by UniProt
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参照データベース
- Entrez Gene: 1791 Human
- Omim: 187410 Human
- SwissProt: P04053 Human
- Unigene: 534206 Human
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別名
- Deoxynucleotidyltransferase terminal antibody
- DNA nucleotidylexotransferase antibody
- DNTT antibody
see all
画像
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![Western blot - Anti-TdT antibody [41A] (ab68886)](http://a.abcam.com/ps/datasheet/Images/68/ab68886/ab68886_1.jpg)
Western blot - Anti-TdT antibody [41A] (ab68886)Anti-TdT antibody [41A] (ab68886) at 1/100 dilution + Thymus extracts
Predicted band size: 58 kDa
Observed band size: 60 kDa (why is the actual band size different from the predicted?) -
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TdT antibody [41A] (ab68886)](http://a.abcam.com/ps/datasheet/Images/68/ab68886/ab68886_2.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TdT antibody [41A] (ab68886)Ab68886 (1:100) staining human TdT in human thymus by immunohistochemistry using formalin fixed, paraffin embedded tissue. -
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TdT antibody [41A] (ab68886)](http://a.abcam.com/ps/datasheet/Images/68/ab68886/ab68886_3.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TdT antibody [41A] (ab68886)Ab68886 (1:100) staining TdT in human thymus tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.
参考文献
This product has been referenced in:
- McClory S et al. Evidence for a stepwise program of extrathymic T cell development within the human tonsil. J Clin Invest 122:1403-15 (2012). IHC ; Human . Read more (PubMed: 22378041) »
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"