製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to TDRD3
  • アプリケーション
    適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region between residues 400 and 450 of Human TDRD3 (NP_110421.1)

  • ポジティブ・コントロール
    • HeLa whole cell lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7-8
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab95878 was affinity purified using an epitope specific to TDRD3 immobilized on solid support.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab95878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at 2-5 µg/mg of lysate.
  • 追加情報
    Is unsuitable for WB.
  • ターゲット情報

    • 機能
      Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.
    • 組織特異性
      Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
    • 配列類似性
      Contains 1 Tudor domain.
      Contains 1 UBA domain.
    • ドメイン
      The Tudor domain specifically recognizes and binds asymmetric dimethylation of histone H3 'Arg-17' (H3R17me2a) and histones H4 'Arg-3', 2 tags for epigenetic transcriptional activation.
    • 細胞内局在
      Cytoplasm. Nucleus. Predominantly cytoplasmic. Associated with actively translating polyribosomes and with mRNA stress granules.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 4732418C03Rik antibody
      • 6720468N18 antibody
      • FLJ21007 antibody
      • OTTHUMP00000018485 antibody
      • TDRD 3 antibody
      • tdrd3 antibody
      • TDRD3_HUMAN antibody
      • Tudor domain containing 3 antibody
      • Tudor domain containing protein 3 antibody
      • Tudor domain-containing protein 3 antibody
      see all

    プロトコール

    参考文献

    ab95878 has not yet been referenced specifically in any publications.

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