Anti-TCR gamma + TCR delta 抗体 [V65] (ab114983)

製品の概要

  • 製品名
    Anti-TCR gamma + TCR delta antibody [V65]
    TCR gamma + TCR delta 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [V65] to TCR gamma + TCR delta
  • アプリケーション
    適用あり: IP, IHC-Fr, Functional Studies, Flow Cytmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    TCR alpha/beta-negative CD3-positive Rat T cell hybridoma III.89.1.4 line.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab114983 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration. in vitro activation, in vivo depletion of gamma/delta T cells.
Flow Cyt Use a concentration of 1 µg/ml. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 関連性
    T cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one a and one b chain or one d and one g chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. The g/d TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most g/d T cells are CD4-/CD8-, some are CD8+. T cells expressing the g/d TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease.
  • 細胞内局在
    Type I membrane protein
  • 参照データベース
  • 別名
    • CD_antigen=CD3d antibody
    • CD3D antibody
    • CD3G antibody
    • T cell antigen receptor delta polypeptide antibody
    • T cell antigen receptor gamma polypeptide antibody
    • T cell rearranging gene gamma antibody
    • T cell receptor delta antibody
    • T cell receptor delta locus antibody
    • T cell receptor gamma antibody
    • T cell receptor gamma chain C region PT gamma 1/2 antibody
    • T cell receptor gamma cluster antibody
    • T cell receptor gamma locus antibody
    • T cell receptor T3 delta chain antibody
    • T cell receptor, delta (V,D,J,C) antibody
    • T cell receptors antibody
    • T cell surface glycoprotein CD3 delta chain antibody
    • T-cell receptor T3 gamma chain antibody
    • T-cell surface glycoprotein CD3 gamma chain antibody
    • T3D antibody
    • T3G antibody
    • TCRD antibody
    • TCRDV1 antibody
    • TCRG antibody
    • TRD antibody
    • TRD locus antibody
    • TRD@ antibody
    • TRG antibody
    • TRG locus antibody
    • TRGC2 antibody
    see all

参考文献

ab114983 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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