Anti-TCR gamma + TCR delta 抗体 [UC7-13D5] (Phycoerythrin) (ab25663)

製品の概要

  • 製品名Anti-TCR gamma + TCR delta antibody [UC7-13D5] (Phycoerythrin)
    TCR gamma + TCR delta 一次抗体 製品一覧
  • 製品の詳細
    Armenian Hamster monoclonal [UC7-13D5] to TCR gamma + TCR delta (Phycoerythrin)
  • 標識Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特異性ab25663 is specific for the gamma-delta heterodimer and plate-bound ab25663 activates gamma-delta TRC-bearing cells. This antibody does not react with alpha-beta TCR-expressing T cells.
  • アプリケーション適用あり: Flow Cyt, IHC-Fr, IP, Celluar Activationmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    The details of the immunogen for this antibody are not available.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25663 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
IHC-Fr
IP
Celluar Activation
  • 追加情報Cellular activation (In vitro activation of γδ TCR-bearing cells): Use at an assay dependent dilution.
    Cellular depletion (In vivo depletion of γδ TCR-expressing T cells): Use at an assay dependent dilution.
    Flow Cyt: Use 0.3µg for 106 cells.
    IHC-Fr: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性T cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one a and one b chain or one d and one g chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. The g/d TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most g/d T cells are CD4-/CD8-, some are CD8+. T cells expressing the g/d TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease.
    • 細胞内局在Type I membrane protein
    • 参照データベース
    • 別名
      • CD_antigen=CD3d antibody
      • CD3D antibody
      • CD3G antibody
      • T cell antigen receptor delta polypeptide antibody
      • T cell antigen receptor gamma polypeptide antibody
      • T cell rearranging gene gamma antibody
      • T cell receptor delta antibody
      • T cell receptor delta locus antibody
      • T cell receptor gamma antibody
      • T cell receptor gamma chain C region PT gamma 1/2 antibody
      • T cell receptor gamma cluster antibody
      • T cell receptor gamma locus antibody
      • T cell receptor T3 delta chain antibody
      • T cell receptor, delta (V,D,J,C) antibody
      • T cell receptors antibody
      • T cell surface glycoprotein CD3 delta chain antibody
      • T-cell receptor T3 gamma chain antibody
      • T-cell surface glycoprotein CD3 gamma chain antibody
      • T3D antibody
      • T3G antibody
      • TCRD antibody
      • TCRDV1 antibody
      • TCRG antibody
      • TRD antibody
      • TRD locus antibody
      • TRD@ antibody
      • TRG antibody
      • TRG locus antibody
      • TRGC2 antibody
      see all

    Anti-TCR gamma + TCR delta antibody [UC7-13D5] (Phycoerythrin) (ab25663) 使用論文

    This product has been referenced in:

    See all 4 Publications for this product

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    There are currently no Abreviews or Questions for ab25663.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"