Anti-TCR alpha + TCR beta 抗体 [H57-597] (PE/Cy5.5 ®) (ab25682)

製品の概要

  • 製品名Anti-TCR alpha + TCR beta antibody [H57-597] (PE/Cy5.5 ®)
    TCR alpha + TCR beta 一次抗体 製品一覧
  • 製品の詳細
    Armenian Hamster monoclonal [H57-597] to TCR alpha + TCR beta (PE/Cy5.5 ®)
  • 標識PE/Cy5.5 ®. Ex: 496nm, Em: 690nm
  • 特異性This antibody does not react with gamma delta TCR bearing cells.
  • アプリケーション適用あり: Flow Cyt, IHC-Fr, IPmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Full length, affinity purified, native TCR protein from mouse hybridoma DO-11.10.

  • エピトープThis antibody reacts with the common epitope of the beta chain of the mouse alpha beta T cell receptor complex.
  • 特記事項This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.


    In vitro and in vivo, this antibody can induce immature thymocytes to undergo apoptosis. In vivo administration of this antibody has been shown to deplete alpha beta TCR bearing cells to near completion and prevent graft rejection. This antibody has also been shown to be useful in studies of 'in vitro' stimulation of alpha beta TCR expressing T cells, and 'in vitro' and 'in vivo' depletion of alpha beta bearing TCR bearing cells.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 16% Sucrose, PBS and stabilizing agent.
  • Concentration information loading...
  • 精製度IgG fraction
  • 一次抗体 備考In vitro and in vivo, this antibody can induce immature thymocytes to undergo apoptosis. In vivo administration of this antibody has been shown to deplete alpha beta TCR bearing cells to near completion and prevent graft rejection. This antibody has also been shown to be useful in studies of 'in vitro' stimulation of alpha beta TCR expressing T cells, and 'in vitro' and 'in vivo' depletion of alpha beta bearing TCR bearing cells.
  • ポリ/モノモノクローナル
  • クローン名H57-597
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab25682 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 0.2µg for 106 cells.
IHC-Fr Use at an assay dependent dilution.
IP Use at an assay dependent dilution.

ターゲット情報

  • 関連性The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
  • 細胞内局在Type I membrane protein.
  • 参照データベース
  • 別名
    • FLJ22602 antibody
    • MGC117436 antibody
    • MGC22624 antibody
    • MGC23964 antibody
    • MGC71411 antibody
    • T cell antigen receptor alpha polypeptide antibody
    • T cell antigen receptor beta polypeptide T cell receptor beta cluster antibody
    • T cell receptor alpha (V D J C) antibody
    • T cell receptor alpha chain C region antibody
    • T cell receptor alpha constant antibody
    • T cell receptor alpha locus antibody
    • T cell receptor beta cluster antibody
    • T cell receptor beta locus antibody
    • TCRA antibody
    • TCRB antibody
    • TCRD antibody
    • TRA antibody
    • TRAC antibody
    • TRB antibody
    see all

Anti-TCR alpha + TCR beta antibody [H57-597] (PE/Cy5.5 ®) (ab25682) 使用論文

ab25682 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"