Anti-TCR alpha + TCR beta 抗体 [H57-597] (FITC) (ab25010)

製品の概要

  • 製品名Anti-TCR alpha + TCR beta antibody [H57-597] (FITC)
    TCR alpha + TCR beta 一次抗体 製品一覧
  • 製品の詳細
    Armenian Hamster monoclonal [H57-597] to TCR alpha + TCR beta (FITC)
  • 標識FITC. Ex: 493nm, Em: 528nm
  • 特異性Common epitope of the ß chain of the mouse aß T cell receptor (TCR) complex
  • アプリケーション適用あり: Flow Cyt, IHC-Fr, IPmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    TCR affinity purified from T-cell hybridoma DO-11.10 (Mouse)

  • 特記事項


    ab25010 can be used for in vitro stimulation of alpha beta TCR-expressing T cells and in vitro and in vivo depletion of aß TCR-bearing cells. Plate-bound or soluble ab25010 activates aß TCR bearing T cells.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 一次抗体 備考ab25010 can be used for in vitro stimulation of alpha beta TCR-expressing T cells and in vitro and in vivo depletion of aß TCR-bearing cells. Plate-bound or soluble ab25010 activates aß TCR bearing T cells.
  • ポリ/モノモノクローナル
  • クローン名H57-597
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab25010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 2µg for 106 cells.
IHC-Fr Use at an assay dependent dilution.
IP Use at an assay dependent dilution.

ターゲット情報

  • 関連性The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
  • 細胞内局在Type I membrane protein.
  • 参照データベース
  • 別名
    • FLJ22602 antibody
    • MGC117436 antibody
    • MGC22624 antibody
    • MGC23964 antibody
    • MGC71411 antibody
    • T cell antigen receptor alpha polypeptide antibody
    • T cell antigen receptor beta polypeptide T cell receptor beta cluster antibody
    • T cell receptor alpha (V D J C) antibody
    • T cell receptor alpha chain C region antibody
    • T cell receptor alpha constant antibody
    • T cell receptor alpha locus antibody
    • T cell receptor beta cluster antibody
    • T cell receptor beta locus antibody
    • TCRA antibody
    • TCRB antibody
    • TCRD antibody
    • TRA antibody
    • TRAC antibody
    • TRB antibody
    see all

Anti-TCR alpha + TCR beta antibody [H57-597] (FITC) 画像

  • ab25010, Hamster monoclonal [H57-597] to TCR alpha + TCR beta (FITC), staining mouse (BALB/c) splenocytes by flow cytometry. 1µg antibody was used / 106 cells. The cells were double stained with a PE-conjugated rat anti-mouse CD19 and then analysed on a FACScan flow cytometer.

Anti-TCR alpha + TCR beta antibody [H57-597] (FITC) (ab25010) 使用論文

This product has been referenced in:
  • Kubo RT  et al. Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. J Immunol 142:2736-42 (1989). Read more (PubMed: 2467936) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"