製品の概要

  • 製品名Anti-Tcl1 antibody
    Tcl1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to Tcl1
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human Tcl1 protein (AAH14024.1).

  • ポジティブ・コントロール
    • Human spleen tissue lysate, Tcl1 transfected 293T cell line, HeLa cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 13 kDa.
ICC/IF Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
  • 組織特異性Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation.
  • 関連疾患Note=Chromosomal aberrations activating TCL1A are found in chronic T-cell leukemias (T-CLL). Translocation t(14;14)(q11;q32); translocation t(7;14)(q35;q32); inversion inv(14)(q11;q32) that involves the T-cell receptor alpha/delta loci.
  • 配列類似性Belongs to the TCL1 family.
  • 細胞内局在Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum. Microsomal fraction.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Anti TCL1A antibody
    • Lymphoma/leukemia, T-cell antibody
    • Oncogene TCL-1 antibody
    • Oncogene TCL1 antibody
    • P14 TCL1 antibody
    • P14 TCL1 protein antibody
    • Protein p14 TCL1 antibody
    • T cell leukemia 1 antibody
    • T cell lymphoma 1 antibody
    • T cell lymphoma 1A antibody
    • T-cell leukemia/lymphoma protein 1A antibody
    • TCL 1 protein antibody
    • TCL1 antibody
    • TCL1 oncogene antibody
    • TCL1 PEN antibody
    • Tcl1a antibody
    • TCL1A antibody antibody
    • TCL1A_HUMAN antibody
    see all

Anti-Tcl1 antibody 画像

  • Anti-Tcl1 antibody (ab88602) at 1 µg/ml + Human spleen tissue lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 13 kDa
    Observed band size : 13 kDa
  • All lanes : Anti-Tcl1 antibody (ab88602) at 1 µg/ml

    Lane 1 : cell lysate from Tcl1 transfected 293T cells
    Lane 2 : cell lysate from non transfected 293T cells

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 13 kDa
    Observed band size : ~13 kDa (why is the actual band size different from the predicted?)
  • ab88602 at 10 µg/ml detecting Tcl1 in paraformaldehyde fixed, permeabilised HeLa cells by immunofluorescence.

Anti-Tcl1 antibody (ab88602) 使用論文

ab88602 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"