製品の概要
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製品名Anti-Tbx4 antibody
Tbx4 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to Tbx4
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由来種Rabbit
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アプリケーション適用あり: WBmore details
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種交差性交差種: Human
交差が予測される動物種: Mouse, Rat, Sheep, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog
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免疫原
Synthetic peptide within Human Tbx4 aa 257-306 (internal sequence). The exact sequence is proprietary.
Sequence:LRVARLQSKEYPVISKSIMRQRLISPQLSATPDVGPLLGTHQALQHYQHE
Database link: P57082 -
ポジティブ･コントロール
- HepG2 cell lysate.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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バッファーPreservative: None
Constituents: 2% Sucrose, PBS -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
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Positive Controls
アプリケーション
Our Abpromise guarantee covers the use of ab28634 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 0.5 µg/ml. Predicted molecular weight: 60 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T. |
ターゲット情報
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機能Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
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関連疾患Defects in TBX4 are the cause of small patella syndrome (SPS) [MIM:147891]; also known as ischiopatellar dysplasia or Scott-Taor syndrome. SPS is an autosomal dominant skeletal dysplasia characterized by patellar aplasia or hypoplasia and by anomalies of the pelvis and feet, including disrupted ossification of the ischia and inferior pubic rami.
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配列類似性Contains 1 T-box DNA-binding domain.
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細胞内局在Nucleus.
- Information by UniProt
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参照データベース
- Entrez Gene: 9496 Human
- Entrez Gene: 21387 Mouse
- Entrez Gene: 303399 Rat
- Omim: 601719 Human
- SwissProt: Q861Q9 Dog
- SwissProt: P57082 Human
- SwissProt: P70325 Mouse
- Unigene: 143907 Human
see all -
別名
- SPS antibody
- T box 4 antibody
- T box protein 4 antibody
see all
画像
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Western blot - Anti-Tbx4 antibody (ab28634)Anti-Tbx4 antibody (ab28634) at 0.5 µg/ml + HepG2 cell lysate 10ug.
Secondary
HRP conjugated anti-Rabbit IgG at 1: 50,000 - 100,000
Predicted band size: 60 kDa
Observed band size: 59 kDa (why is the actual band size different from the predicted?)
プロトコール
参考文献
This product has been referenced in:
- Osz K et al. The thrombospondin-1 receptor CD36 is an important mediator of ovarian angiogenesis and folliculogenesis. Reprod Biol Endocrinol 12:21 (2014). IHC . Read more (PubMed: 24628875) »
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"