Anti-TBX1 抗体 - Carboxyterminal end (ab65935)

製品の概要

  • 製品名Anti-TBX1 antibody - Carboxyterminal end
    TBX1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TBX1 - Carboxyterminal end
  • 特異性Detects endogenous levels of total TBX1 protein.
  • アプリケーション適用あり: ELISA, ICC/IF, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide derived from C-terminal of human TBX1.

  • ポジティブ・コントロール
    • A549 cells, extracts from COLO205 cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab65935 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
ICC/IF
WB
  • 追加情報ELISA: 1/20000.
    ICC/IF: 1/500 - 1/1000.
    WB: 1/500 - 1/1000. Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries.
    • 関連疾患Haploinsufficiency of the TBX1 gene is responsible for most of the physical malformations present in DiGeorge syndrome (DGS) and velocardiofacial syndrome (VCFS) [MIM:188400, 192430]. DGS is characterized by the association of several malformations: hypoplastic thymus and parathyroid glands, congenital conotruncal cardiopathy, and a subtle but characteristic facial dysmorphology. VCFS is marked by the association of congenital conotruncal heart defects, cleft palate or velar insufficiency, facial dysmorpholgy and learning difficulties. It is now accepted that these two syndromes represent two forms of clinical expression of the same entity manifesting at different stages of life.
      Defects in TBX1 are a cause of DiGeorge syndrome (DGS) [MIM:188400].
      Defects in TBX1 are a cause of velocardiofacial syndrome (VCFS) [MIM:192430].
      Defects in TBX1 are a cause of conotruncal heart malformations (CTHM) [MIM:217095]. CTHM consist of cardiac outflow tract defects, such as tetralogy of Fallot, pulmonary atresia, double-outlet right ventricle, truncus arteriosus communis, and aortic arch anomalies.
    • 配列類似性Contains 1 T-box DNA-binding domain.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Brachyury antibody
      • CAFS antibody
      • CTHM antibody
      • DGCR antibody
      • DGS antibody
      • DORV antibody
      • T box antibody
      • T box 1 antibody
      • T box 1 transcription factor antibody
      • T box 1 transcription factor C antibody
      • T box protein 1 antibody
      • T box transcription factor TBX 1 antibody
      • T box transcription factor TBX1 antibody
      • T-box protein 1 antibody
      • T-box transcription factor TBX1 antibody
      • TBX 1 antibody
      • TBX 1C antibody
      • tbx1 antibody
      • TBX1_HUMAN antibody
      • TBX1C antibody
      • Testis specific T box protein antibody
      • Testis-specific T-box protein antibody
      • TGA antibody
      • VCFS antibody
      see all

    Anti-TBX1 antibody - Carboxyterminal end 画像

    • All lanes : Anti-TBX1 antibody - Carboxyterminal end (ab65935) at 1/500 dilution

      Lane 1 : extracts from COLO205 cells
      Lane 2 : extracts from COLO205 cells with immunizing peptide at 10 µg

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 44 kDa
      Observed band size : 44 kDa
    • ab65935 at 1/500 dilution staining A549 cells without (left) and with (right) immunizing peptide.

    Anti-TBX1 antibody - Carboxyterminal end (ab65935) 使用論文

    ab65935 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab65935.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"