製品の概要

  • 製品名Anti-TBX1 antibody
    TBX1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TBX1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Rabbit, Guinea pig, Cat
  • 免疫原

    Synthetic peptide within residues: PVASPTQPSG TEKGGHVLKD KEVKAETSRN TPEREVELLR DAGGCVNLGL, corresponding to internal sequence amino acids 324-373 of Human TBX1 (NP_542377)

  • ポジティブ・コントロール
    • Human fetal lung lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84730 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries.
  • 関連疾患Haploinsufficiency of the TBX1 gene is responsible for most of the physical malformations present in DiGeorge syndrome (DGS) and velocardiofacial syndrome (VCFS) [MIM:188400, 192430]. DGS is characterized by the association of several malformations: hypoplastic thymus and parathyroid glands, congenital conotruncal cardiopathy, and a subtle but characteristic facial dysmorphology. VCFS is marked by the association of congenital conotruncal heart defects, cleft palate or velar insufficiency, facial dysmorpholgy and learning difficulties. It is now accepted that these two syndromes represent two forms of clinical expression of the same entity manifesting at different stages of life.
    Defects in TBX1 are a cause of DiGeorge syndrome (DGS) [MIM:188400].
    Defects in TBX1 are a cause of velocardiofacial syndrome (VCFS) [MIM:192430].
    Defects in TBX1 are a cause of conotruncal heart malformations (CTHM) [MIM:217095]. CTHM consist of cardiac outflow tract defects, such as tetralogy of Fallot, pulmonary atresia, double-outlet right ventricle, truncus arteriosus communis, and aortic arch anomalies.
  • 配列類似性Contains 1 T-box DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Brachyury antibody
    • CAFS antibody
    • CTHM antibody
    • DGCR antibody
    • DGS antibody
    • DORV antibody
    • T box antibody
    • T box 1 antibody
    • T box 1 transcription factor antibody
    • T box 1 transcription factor C antibody
    • T box protein 1 antibody
    • T box transcription factor TBX 1 antibody
    • T box transcription factor TBX1 antibody
    • T-box protein 1 antibody
    • T-box transcription factor TBX1 antibody
    • TBX 1 antibody
    • TBX 1C antibody
    • tbx1 antibody
    • TBX1_HUMAN antibody
    • TBX1C antibody
    • Testis specific T box protein antibody
    • Testis-specific T-box protein antibody
    • TGA antibody
    • VCFS antibody
    see all

Anti-TBX1 antibody 画像

  • Anti-TBX1 antibody (ab84730) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal lung lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 43 kDa
    Observed band size : 43 kDa

Anti-TBX1 antibody (ab84730) 使用論文

ab84730 has not yet been referenced specifically in any publications.

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We do not have a different lot of this. We have not received other complaints but I recommend trying a different antibody. Are you interested in the rabbit monoclonal ab109313 as a free replacement? The w...

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Thank you for your patience in this matter. I have talked to the lab and we are able to provide more of lot#906622, although the lot number will be different on the vial you receive, it will be the same product. The reason for this is that we c...

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Thank you for contacting Abcam. I am in contact with the lab about whether we have more of ab84730, lot#906622 in the freezers, as we are showing that we do not have any ab84730 in stock. I will let you know as soon as I hear anything.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"