製品の概要

  • 製品名Anti-TBCD antibody
    TBCD 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TBCD
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide, corresponding to a region within internal sequence amino acids 299-348 (KLVQRLGLTF LKPKVAAWRY QRGCRSLAAN LQLLTQGQSE QKPLILTEDD) of Human TBCD (NM_005993).

  • ポジティブ・コントロール
    • HeLa cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab116519 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 133 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Tubulin-folding protein; involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Acts as a GTPase-activating protein (GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.
  • 組織特異性Ubiquitously expressed.
  • 配列類似性Belongs to the TBCD family.
    Contains 3 HEAT repeats.
  • 細胞内局在Cell junction > tight junction. Lateral cell membrane. Cytoplasm. Cell junction > adherens junction. Localized in cell-cell contacts.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Beta tubulin cofactor D antibody
    • Beta-tubulin cofactor D antibody
    • KIAA0988 antibody
    • SSD 1 antibody
    • SSD-1 antibody
    • SSD1 antibody
    • tbcd antibody
    • TBCD_HUMAN antibody
    • tfcD antibody
    • Tubulin folding cofactor D antibody
    • Tubulin specific chaperone D antibody
    • Tubulin-folding cofactor D antibody
    • Tubulin-specific chaperone D antibody
    see all

Anti-TBCD antibody 画像

  • Anti-TBCD antibody (ab116519) at 1 µg/ml + HeLa cell lysate at 10 µg

    Predicted band size : 133 kDa

Anti-TBCD antibody (ab116519) 使用論文

ab116519 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"