Rabbit polyclonal to Tapasin
Sheep, Horse, Pig, African green monkey
Synthetic peptide corresponding to a region within internal sequence amino acids 359-408 (SVSLSGHLQP PPVTTEQHGA RYACRIHHPS LPASGRSAEV TLEVAGLSGP) of Human Tapasin (NP_003181).
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
Neutrophils, mostly in fully differentiated cells.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
The N-terminus is required for efficient association with MHC class I molecule and for a stable interaction between MHC I and calreticulin. Binding to TAP is mediated by the C-terminus region.
Endoplasmic reticulum membrane.
Information by UniProt
- NGS 17 antibody
- NGS-17 antibody
- NGS17 antibody
has not yet been referenced specifically in any publications.
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