製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Tapasin
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Sheep, Horse, Pig, African green monkey
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 359-408 (SVSLSGHLQP PPVTTEQHGA RYACRIHHPS LPASGRSAEV TLEVAGLSGP) of Human Tapasin (NP_003181).

  • ポジティブ・コントロール
    • OVCAR-3 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab104806 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
  • 組織特異性
    Neutrophils, mostly in fully differentiated cells.
  • 配列類似性
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • ドメイン
    The N-terminus is required for efficient association with MHC class I molecule and for a stable interaction between MHC I and calreticulin. Binding to TAP is mediated by the C-terminus region.
  • 細胞内局在
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • NGS 17 antibody
    • NGS-17 antibody
    • NGS17 antibody
    • TAP associated protein antibody
    • TAP binding protein antibody
    • TAP binding protein (tapasin) antibody
    • TAP BP antibody
    • TAP-associated protein antibody
    • TAP-binding protein antibody
    • TAPA antibody
    • Tapasin antibody
    • TAPBP antibody
    • TPN antibody
    • TPSN antibody
    • TPSN_HUMAN antibody
    see all

画像

  • Anti-Tapasin antibody (ab104806) at 1 µg/ml + OVCAR-3 cell lysate at 10 µg

    Predicted band size : 48 kDa

プロトコール

参考文献

ab104806 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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