Anti-TAPA1 抗体 [Eat 2] (Phycoerythrin) (ab23553)

製品の概要

  • 製品名Anti-TAPA1 antibody [Eat 2] (Phycoerythrin)
    TAPA1 一次抗体 製品一覧
  • 製品の詳細
    Armenian Hamster monoclonal [Eat 2] to TAPA1 (Phycoerythrin)
  • 標識Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特異性ab23553 recognises CD81, a 26kD cell surface glycoprotein that is also known as TAPA-1.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Mouse, Rat
  • 免疫原

    Tissue/ cell preparation: 38C13, murine B cell line.

  • 特記事項Myeloma: Spleen cells from immunised Armenian hamsters were fused with cells of the mouse PX3-Ag.8.653 myeloma cell line.

    Purified IgG conjugated to R. Phycoerythrin (RPE).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab23553 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報Flow Cyt: 1/neat.
    Use 10µl for 106 cells in 100µl.

    Note: ab23553 induces homotypic aggregation of B cells and inhibits anti Ig and IL4 induced proliferation. ab23553 requires the presence of both extracellular loops of TAPA1 for binding.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May acts a the viral receptor for HCV.
    • 組織特異性Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.
    • 関連疾患Defects in CD81 are the cause of immunodeficiency common variable type 6 (CVID6) [MIM:613496]; also called antibody deficiency due to CD81 defect. CVID6 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
    • 配列類似性Belongs to the tetraspanin (TM4SF) family.
    • 翻訳後修飾Not glycosylated.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 26 kDa cell surface protein TAPA 1 antibody
      • 26 kDa cell surface protein TAPA-1 antibody
      • 26 kDa cell surface protein TAPA1 antibody
      • CD 81 antibody
      • CD81 antibody
      • CD81 antigen (target of antiproliferative antibody 1) antibody
      • CD81 antigen antibody
      • CD81 molecule antibody
      • CD81_HUMAN antibody
      • CVID6 antibody
      • S5.7 antibody
      • TAPA 1 antibody
      • TAPA1 antibody
      • Target of the antiproliferative antibody 1 antibody
      • Tetraspanin 28 antibody
      • Tetraspanin-28 antibody
      • Tetraspanin28 antibody
      • Tspan 28 antibody
      • Tspan-28 antibody
      • Tspan28 antibody
      see all

    Anti-TAPA1 antibody [Eat 2] (Phycoerythrin) (ab23553) 使用論文

    ab23553 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"