製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to TANK
  • アプリケーション
    適用あり: WB, ICCmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:- a 14 amino acid peptide from near the amino terminus of human TANK

  • ポジティブ・コントロール
    • Daudi Cell Lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab47633 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 47 kDa.
ICC Use a concentration of 2.5 µg/ml.

ターゲット情報

  • 機能
    Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Contains 1 C2H2-type zinc finger.
  • 翻訳後修飾
    Phosphorylated by IKBKE.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • I TRAF antibody
    • I-TRAF antibody
    • ITRAF antibody
    • Tank antibody
    • TANK_HUMAN antibody
    • TRAF family member associated NF KAPPA B activator antibody
    • TRAF family member associated NFKB activator antibody
    • TRAF family member-associated NF-kappa-B activator antibody
    • TRAF interacting protein antibody
    • TRAF interacting protein TANK isoform a antibody
    • TRAF interacting protein TANK isoform b antibody
    • TRAF-interacting protein antibody
    • TRAF2 antibody
    see all

画像

  • Lane 1 : Anti-TANK antibody (ab47633) at 0.5 µg/ml
    Lane 2 : Anti-TANK antibody (ab47633) at 1 µg/ml

    Lane 1 : Daudi cell lysate at 15 µg per lane.
    Lane 2 : Daudi cell lysate at 15 µg per lane.

    Secondary
    Anti-rabbit IgG HRP at 1:10000

    Predicted band size : 47 kDa
    Observed band size : 52 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 38 kDa. We are unsure as to the identity of these extra bands.
  • ab47633 at 2.5ug/ml staining TANK in Daudi cells by Immunocytochemistry.

参考文献

ab47633 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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