製品の概要

  • 製品名Anti-TAF15 antibody
    TAF15 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TAF15
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to a region within amino acids 200-250 of Human TAF15 (Swiss-Prot Q92804).

  • ポジティブ・コントロール
    • Human stomach adenocarcinoma

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84369 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/100 - 1/500.
    Antigen exposure is recommended.
    Antigen exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II).
    • 組織特異性Ubiquitous. Observed in all fetal and adult tissues.
    • 関連疾患Note=A chromosomal aberration involving TAF15/TAF2N is found in a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with NR4A3.
    • 配列類似性Belongs to the RRM TET family.
      Contains 1 RanBP2-type zinc finger.
      Contains 1 RRM (RNA recognition motif) domain.
    • 翻訳後修飾Dimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine. The methylation may favor nuclear localization and positive regulation of TAF15 transcriptional activity.
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在Nucleus. Cytoplasm. Shuttles from the nucleus to the cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 68 kDa TATA-binding protein-associated factor antibody
      • Npl3 antibody
      • RBP56 antibody
      • RBP56_HUMAN antibody
      • RNA binding protein 56 antibody
      • RNA-binding protein 56 antibody
      • TAF antibody
      • TAF(II)68 antibody
      • TAF15 antibody
      • TAF15 RNA polymerase II TATA box binding protein (TBP) associated factor 68kDa antibody
      • TAF2N antibody
      • TAFII68 antibody
      • TATA-binding protein-associated factor 2N antibody
      see all

    Anti-TAF15 antibody 画像

    • ab84369 at 1/250, staining human TAF15 in a section of human stomach adenocarcinoma by immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection: DAB staining using anti-rabbit antibody at 1/100.

    Anti-TAF15 antibody (ab84369) 使用論文

    ab84369 has not yet been referenced specifically in any publications.

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