製品の概要

  • 製品名Anti-TAF15 antibody
    TAF15 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TAF15
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Cow, Dog, Pig, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan
  • 免疫原

    Synthetic peptide corresponding to region between residue 550 and the C-terminus (residue 592) of Human TAF15 (Swiss-Prot entry Q92804)

  • ポジティブ・コントロール
    • Whole cell lysate from 293T cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab70390 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IP
  • 追加情報IP: Use at 1 - 4 µg/mg of lysate.
    WB: 1/10000 - 1/30000. Detects a band of approximately 66 kDa (predicted molecular weight: 62 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II).
    • 組織特異性Ubiquitous. Observed in all fetal and adult tissues.
    • 関連疾患Note=A chromosomal aberration involving TAF15/TAF2N is found in a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with NR4A3.
    • 配列類似性Belongs to the RRM TET family.
      Contains 1 RanBP2-type zinc finger.
      Contains 1 RRM (RNA recognition motif) domain.
    • 翻訳後修飾Dimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine. The methylation may favor nuclear localization and positive regulation of TAF15 transcriptional activity.
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在Nucleus. Cytoplasm. Shuttles from the nucleus to the cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 68 kDa TATA-binding protein-associated factor antibody
      • Npl3 antibody
      • RBP56 antibody
      • RBP56_HUMAN antibody
      • RNA binding protein 56 antibody
      • RNA-binding protein 56 antibody
      • TAF antibody
      • TAF(II)68 antibody
      • TAF15 antibody
      • TAF15 RNA polymerase II TATA box binding protein (TBP) associated factor 68kDa antibody
      • TAF2N antibody
      • TAFII68 antibody
      • TATA-binding protein-associated factor 2N antibody
      see all

    Anti-TAF15 antibody 画像

    • Anti-TAF15 antibody (ab70390) at 1/20000 dilution + Whole cell lysate from 293T cells at 200 µg
      Developed using the ECL technique

      Predicted band size : 62 kDa
      Observed band size : 66 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 80 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 5 seconds

    Anti-TAF15 antibody (ab70390) 使用論文

    ab70390 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab70390.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"