製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to TACC1
  • アプリケーション
    適用あり: IP, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    CPELVPSRRSKLRKPKP

    , corresponding to amino acids 219-235 of Human TACC1.

  • ポジティブ・コントロール
    • HeLa whole cell lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    pH: 8.00
    Preservative: 0.05% Sodium azide
    Constituents: 2.42% Tris, 0.0292% EDTA, 30% Glycerol, 8.7% Sodium chloride
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab17915 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP
WB
  • 追加情報
    IP: Use at an assay dependent dilution.
    WB: Use at a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 125 and 55 kDa (predicted molecular weight: 90 kDa, there are several other isoforms).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.
    • 組織特異性
      Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer.
    • 配列類似性
      Belongs to the TACC family.
      Contains 2 SPAZ (Ser/Pro-rich AZU-1) domains.
    • 発生段階
      Expressed at high level during early embryogenesis.
    • 翻訳後修飾
      Isoform 1 is heavily phosphorylated; isoform 6 is not. Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在
      Cytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome. Nucleus during interphase. Weakly concentrated at centrosomes during mitosis and colocalizes with AURKC at the midbody during cytokinesis.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZp686K18126 antibody
      • Ga 55 antibody
      • Ga55 antibody
      • Gastric cancer antigen Ga 55 antibody
      • Gastric cancer antigen Ga55 antibody
      • KIAA1103 antibody
      • TACC 1 antibody
      • Tacc1 antibody
      • TACC1_HUMAN antibody
      • Taxin 1 antibody
      • Taxin-1 antibody
      • Taxin1 antibody
      • Transforming acidic coiled coil containing protein 1 antibody
      • Transforming acidic coiled-coil-containing protein 1 antibody
      see all

    参考文献

    ab17915 has not yet been referenced specifically in any publications.

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab17915.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    登録