製品の概要

  • 製品名Anti-T-bet / Tbx21 antibody
    T-bet / Tbx21 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to T-bet / Tbx21
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Horse, Cow, Dog, Chimpanzee, Macaque Monkey
  • 免疫原

    Recombinant fragment: LGAPRDHSYE AEFRAVSMKP AFLPSAPGPT MSYYRGQEVL APGAGWPVAP QYPPKMGPAS WFRPMRTLPM EPGPGGSEGR GPEDQGPPLV WTEIAPIRPE , corresponding to amino acids 387-486 of Human T-bet/ Tbx21 (AAH39739) with a proprietary tag

  • ポジティブ・コントロール
    • NIH 3T3 cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab88114 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 58 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs.
  • 組織特異性T-cell specific.
  • 関連疾患Genetic variations in TBX21 are associated with susceptibility to asthma with nasal polyps and aspirin intolerance (ANPAI) [MIM:208550]. A condition consisting of asthma, aspirin sensitivity and nasal polyposis. Nasal polyposis is due to chronic inflammation of the paranasal sinus mucosa, leading to protrusion of edematous polyps into the nasal cavities.
  • 配列類似性Contains 1 T-box DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • T bet antibody
    • T box 21 antibody
    • T box expressed in T cells antibody
    • T box protein 21 antibody
    • T box transcription factor TBX21 antibody
    • T cell specific T box transcription factor antibody
    • T cell specific T box transcription factor T bet antibody
    • T PET antibody
    • T-box protein 21 antibody
    • T-box transcription factor TBX21 antibody
    • T-cell-specific T-box transcription factor T-bet antibody
    • TBET antibody
    • TBLYM antibody
    • TBX 21 antibody
    • Tbx21 antibody
    • TBX21_HUMAN antibody
    • TPET antibody
    • Transcription factor TBLYM antibody
    see all

Anti-T-bet / Tbx21 antibody 画像

  • Anti-T-bet / Tbx21 antibody (ab88114) at 1 µg/ml + immunogen (tagged recombinant fragment) at 0.2 µg

    Secondary
    Goat anti-Mouse IgG at 1/5000 dilution

    Predicted band size : 58 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • Anti-T-bet / Tbx21 antibody (ab88114) at 1 µg/ml + NIH 3T3 cell lysate at 25 µg

    Secondary
    Goat anti-Mouse IgG at 1/5000 dilution

    Predicted band size : 58 kDa

Anti-T-bet / Tbx21 antibody (ab88114) 使用論文

This product has been referenced in:
  • Singh SP  et al. Prenatal secondhand cigarette smoke promotes Th2 polarization and impairs goblet cell differentiation and airway mucus formation. J Immunol 187:4542-52 (2011). WB ; Mouse . Read more (PubMed: 21930963) »
  • Yang P  et al. The mutations of Th1 cell-specific T-box transcription factor may be associated with a predominant Th2 phenotype in gastric cancers. Int J Immunogenet 37:111-5 (2010). Read more (PubMed: 20193034) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab88114.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"