製品の概要

  • 製品名
    Anti-Syntrophin gamma 2 antibody
    Syntrophin gamma 2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Syntrophin gamma 2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide: DSQSLARKYMYSS, corresponding to C terminal amino acids 527-539 of Syntrophin gamma 2.

  • ポジティブ・コントロール
    • Human duodenum and ileum lysate. Preliminary experiments gave ~28kDa and 20kDa bands in Human brain and human testis lysates

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    Purified from goat serum by ammonium sulphate precipitation followed by immunogen affinity chromatography.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab15713 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.1 - 3 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 62 kDa).Can be blocked with Human Syntrophin gamma 2 peptide (ab23267).

ターゲット情報

  • 機能
    Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.
  • 組織特異性
    Widely expressed. Strong expression in brain and testis. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia.
  • 配列類似性
    Belongs to the syntrophin family.
    Contains 1 PDZ (DHR) domain.
    Contains 1 PH domain.
  • ドメイン
    The association with dystrophin or related proteins probably leaves the PDZ domain available to recruit proteins to the membrane.
  • 細胞内局在
    Cell membrane > sarcolemma. Cytoplasm > cytoskeleton. In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 9530013L23 antibody
    • G2SYN antibody
    • Gamma-2-syntrophin antibody
    • Gamma2-syntrophin antibody
    • SNTG2 antibody
    • SNTG2_HUMAN antibody
    • SYN5 antibody
    • Syntrophin 5 antibody
    • Syntrophin-5 antibody
    see all

画像

  • Anti-Syntrophin gamma 2 antibody (ab15713) at 3 µg/ml + lysate prepared from human duodenum tissue, in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 62 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 110 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 1 hour

プロトコール

参考文献

ab15713 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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