製品の概要
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製品名Anti-Syntrophin gamma 2 antibody
Syntrophin gamma 2 一次抗体 製品一覧 -
製品の詳細Goat polyclonal to Syntrophin gamma 2
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アプリケーション適用あり: WBmore details
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種交差性交差種: Human
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免疫原
Synthetic peptide: DSQSLARKYMYSS, corresponding to C terminal amino acids 527-539 of Syntrophin gamma 2.
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ポジティブ･コントロール
- Human duodenum and ileum lysate. Preliminary experiments gave ~28kDa and 20kDa bands in Human brain and human testis lysates
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3 -
Concentration information loading... -
精製度Immunogen affinity purified
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特記事項（精製）Purified from goat serum by ammonium sulphate precipitation followed by immunogen affinity chromatography.
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
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Immunizing Peptide (Blocking)
アプリケーション
Our Abpromise guarantee covers the use of ab15713 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 0.1 - 3 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 62 kDa).Can be blocked with Human Syntrophin gamma 2 peptide (ab23267). |
ターゲット情報
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機能Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.
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組織特異性Widely expressed. Strong expression in brain and testis. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia.
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配列類似性Belongs to the syntrophin family.
Contains 1 PDZ (DHR) domain.
Contains 1 PH domain. -
ドメインThe association with dystrophin or related proteins probably leaves the PDZ domain available to recruit proteins to the membrane.
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細胞内局在Cell membrane > sarcolemma. Cytoplasm > cytoskeleton. In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 54221 Human
- Omim: 608715 Human
- SwissProt: Q9NY99 Human
- Unigene: 595069 Human
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別名
- 9530013L23 antibody
- G2SYN antibody
- Gamma-2-syntrophin antibody
see all
Anti-Syntrophin gamma 2 antibody 画像
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Western blot - Syntrophin gamma 2 antibody (ab15713)Anti-Syntrophin gamma 2 antibody (ab15713) at 3 µg/ml + lysate prepared from human duodenum tissue, in RIPA buffer at 35 µg
Developed using the ECL technique
Predicted band size : 62 kDa
Observed band size : 70 kDa (why is the actual band size different from the predicted?)
Additional bands at : 110 kDa. We are unsure as to the identity of these extra bands.
Exposure time : 1 hour
プロトコール
Anti-Syntrophin gamma 2 antibody (ab15713) 使用論文
ab15713 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"