Anti-Syntaxin 1A + Syntaxin 1B2 抗体 (ab39986)

製品の概要

  • 製品名Anti-Syntaxin 1A + Syntaxin 1B2 antibody
  • 製品の詳細
    Goat polyclonal to Syntaxin 1A + Syntaxin 1B2
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Sheep, Chicken, Cow, Human, Zebrafish
  • 免疫原

    Synthetic peptide:

    KDRTQELRTAKD

    , corresponding to N terminal amino acids 2/13 of Human Syntaxin 1A + Syntaxin 1B2

  • ポジティブ・コントロール
    • Mouse Brain lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab39986 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: Use at an assay dependent dilution. Antibody detection limit dilution 1:32,000
    WB: Use at a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 35 kDa. (predicted molecular weight: 33 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Syntaxins are potentially involved in the docking of synaptic vesicles at presynaptic active zones and may play a key role in neurotransmitter exocytosis. Three isoforms are produced by alternative splicing. Isoform 1 is expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain. Syntaxin 1A interacts with VAPA and SYBU and is a member of the SNARE core complex containing SNAP25 and VAMP2. In addition, it is found in complexes with SNAP25, SNAP23 and VAMP8. Haploinsufficiency of STX1A may result in particular cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome, a rare developmental disorder.
    • 細胞内局在Cell membrane; single-pass type IV membrane protein; Isoform 2 is thought to be secreted
    • 参照データベース
    • 別名
      • adipocyte C1Q and collagen domain containing antibody
      • adiponectin antibody
      • adipose most abundant gene transcript 1 antibody
      • HPC 1 antibody
      • p35 1 antibody
      • STX1 antibody
      • STX1A antibody
      • STX1B1 antibody
      • STX1B2 antibody
      see all

    Anti-Syntaxin 1A + Syntaxin 1B2 antibody 画像

    • Anti-Syntaxin 1A + Syntaxin 1B2 antibody (ab39986) at 0.003 µg/ml (for 1 hour) + Mouse Brain lysate in RIPA buffer at 35 µg
      Developed using the ECL technique

      Predicted band size : 33 kDa
      Observed band size : 35 kDa (why is the actual band size different from the predicted?)

    Anti-Syntaxin 1A + Syntaxin 1B2 antibody (ab39986) 使用論文

    ab39986 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry and your interest in our products. Screening our immunizing antigen against other proteins in BLAST-search (against mammalia), ab39986 seems not to cross-react with syntaxin 3. This antibody has not been tested and charac...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"