製品の概要

  • 製品名Anti-Syntaxin 1a antibody [SP36]
    Syntaxin 1a 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [SP36] to Syntaxin 1a
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to N terminus of human Syntaxin 1a

  • エピトープN terminus
  • ポジティブ・コントロール
    • Human brain tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab73913 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/100 for 30 minutes at room temperature
    Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 minutes, followed by cooling at room temperature for 20 minutes.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
    • 組織特異性Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain.
    • 関連疾患Note=STX1A is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
    • 配列類似性Belongs to the syntaxin family.
      Contains 1 t-SNARE coiled-coil homology domain.
    • 細胞内局在Secreted and Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cell junction > synapse > synaptosome.
    • Information by UniProt
    • 参照データベース
    • 別名
      • HPC 1 antibody
      • Neuron specific antigen HPC1 antibody
      • Neuron-specific antigen HPC-1 antibody
      • OTTHUMP00000174615 antibody
      • OTTHUMP00000174616 antibody
      • OTTHUMP00000174617 antibody
      • OTTHUMP00000174618 antibody
      • P35-1 antibody
      • STX1 antibody
      • STX1A antibody
      • STX1A_HUMAN antibody
      • SYN1A antibody
      • Syntaxin 1A (brain) antibody
      • Syntaxin 1A brain antibody
      • Syntaxin-1A antibody
      see all

    Anti-Syntaxin 1a antibody [SP36] 画像

    • ab73913, at a 1/100 dilution, staining Syntaxin 1a in formalin fixed, paraffin embedded human brain tissue by Immunohistochemistry.

    Anti-Syntaxin 1a antibody [SP36] (ab73913) 使用論文

    ab73913 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"