Anti-Syntaxin 16 抗体 - Drosophila Golgi/Trans-Golgi Marker (ab32340)
Key features and details
- Rabbit polyclonal to Syntaxin 16 - Drosophila Golgi/Trans-Golgi Marker
- Suitable for: WB
- Reacts with: Drosophila melanogaster
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Syntaxin 16 antibody - Drosophila Golgi/Trans-Golgi Marker
Syntaxin 16 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Syntaxin 16 - Drosophila Golgi/Trans-Golgi Marker -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: ICC/IF -
種交差性
交差種: Drosophila melanogaster -
免疫原
Synthetic peptide corresponding to Drosophila melanogaster Syntaxin 16 aa 200-300 conjugated to keyhole limpet haemocyanin.
(Peptide available asab32339) -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab32340の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 2.5 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
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特記事項 |
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WB
Use a concentration of 2.5 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa). |
ターゲット情報
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機能
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. -
組織特異性
Ubiquitous. -
関連疾患
Genetic variations in STX16 may be a cause of pseudohypoparathyroidism type 1B (PHP1B) [MIM:603233]. Pseudohypoparathyroidism refers to a heterogeneous group of disorders characterized by resistance to parathyroid hormone (PTH). PHP1B is characterized by PTH-resistant hypocalcemia and hyperphosphatemia. Patients affected with PHP1B lack developmental defects characteristic of Albright hereditary osteodystrophy, and typically show no other endocrine abnormalities besides resistance to PTH. In some cases microdeletions involving STX16 appear to cause loss of methylation at exon A/B of the GNAS gene, resulting in PHP1B. -
配列類似性
Belongs to the syntaxin family.
Contains 1 t-SNARE coiled-coil homology domain. -
細胞内局在
Cytoplasm and Golgi apparatus membrane. - Information by UniProt
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別名
- hsyn16 antibody
- MGC90328 antibody
- Stx16 antibody
see all
画像
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Anti-Syntaxin 16 antibody - Drosophila Golgi/Trans-Golgi Marker (ab32340) at 1 µg/ml + Schneider L2 whole cell lysate (ab14893) at 20 µg
Secondary
IRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/15000 dilution
Performed under reducing conditions.
Predicted band size: 40 kDa
Observed band size: 40 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (6)
ab32340 は 6 報の論文で使用されています。
- Saito M et al. Role of the Drosophila YATA protein in the proper subcellular localization of COPI revealed by in vivo analysis. Genes Genet Syst 95:303-314 (2021). PubMed: 33583916
- Patel PH et al. Vps54 regulates Drosophila neuromuscular junction development and interacts genetically with Rab7 to control composition of the postsynaptic density. Biol Open 9:N/A (2020). PubMed: 32747448
- Bellec K et al. Stratum recruits Rab8 at Golgi exit sites to regulate the basolateral sorting of Notch and Sanpodo. Development 145:N/A (2018). PubMed: 29967125
- Charng WL et al. Drosophila Tempura, a novel protein prenyltransferase a subunit, regulates notch signaling via Rab1 and Rab11. PLoS Biol 12:e1001777 (2014). ICC/IF ; Drosophila melanogaster . PubMed: 24492843
- Hornbruch-Freitag C et al. Drosophila Swiprosin-1/EFHD2 accumulates at the prefusion complex stage during Drosophila myoblast fusion. J Cell Sci 124:3266-78 (2011). ICC/IF ; Drosophila melanogaster . PubMed: 21896648
- Tiklová K et al. Epithelial septate junction assembly relies on melanotransferrin iron binding and endocytosis in Drosophila. Nat Cell Biol 12:1071-7 (2010). WB, IHC-P ; Drosophila melanogaster . PubMed: 20935638