製品の概要

  • 製品名Anti-Syntaxin 13 antibody [4E212]
    Syntaxin 13 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4E212] to Syntaxin 13
  • 特異性ab18011 identifies recombinant rat syntaxin 13 as an ~38kD protein (corresponding to the predicted band). Additional bands of 27 and 37kD may also be recognized and are believed to correspond to degradation products of syntaxin 13.
  • アプリケーション適用あり: WBmore details
    適用なし: ICC/IF
  • 種交差性
    交差種: Mouse, Rat, Hamster, Dog
  • 免疫原

    Recombinant fragment (Rat Syntaxin 13 cytoplasmic domain).

  • ポジティブ・コントロール
    • Rat or mouse brain extract.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 50% Glycerol, PBS, 0.1mM PMSF
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名4E212
  • ミエローマNS1
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab18011 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa.
  • 追加情報Is unsuitable for ICC/IF.
  • ターゲット情報

    • 関連性Syntaxin 13 is an integral membrane protein that belongs to the t-SNARE family, a group of proteins involved in protein transport. Confocal immunofluoresence and electron microscopy studies have shown that syntaxin 13 is primarily localized to tubular early and recycling endosomes, where it colocalizes with transferrin receptor, and it is also localized in endosomal vacuoles. Syntaxin 13 has been found to be expressed in all tissues, with higher levels of the protein found in brain, lung, spleen, thymus and testes. Immunoprecipitation studies show that syntaxin 13 complexes with beta-SNAP, VAMP2/3, and SNAP25. The binding of this complex to alpha-SNAP and NSF is terminated in the presence of ATP. These results suggest that syntaxin 13 is a SNARE protein which mediates the recycling protein flow through tubulo vesicular recycling endosomes.
    • 細胞内局在Tubular early and recycling endosomes and endosomal vacuoles.
    • 別名
      • Dm Syx13 antibody
      • ff16 antibody
      • Syntaxin13 antibody
      • Syx13 antibody

    Anti-Syntaxin 13 antibody [4E212] (ab18011) 使用論文

    This product has been referenced in:
    • Chung WY  et al. WNK4 inhibits plasma membrane targeting of NCC through regulation of syntaxin13 SNARE formation. Cell Signal 25:2469-77 (2013). Read more (PubMed: 23993962) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"