製品の概要

  • 製品名
    Anti-Synaptotagmin 1 antibody
    Synaptotagmin 1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Synaptotagmin 1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Rat, Xenopus laevis
    非交差種: Mouse
  • 免疫原

    Synthetic peptide derived from sequence near the amino terminus of rat Synaptotagmin 1, conjugated to KLH

  • ポジティブ・コントロール
    • Rat Brain and Xenopus Ovary lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab82414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Detects a band of approximately 65 kDa (predicted molecular weight: 48 kDa).

ターゲット情報

  • 機能
    May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
  • 配列類似性
    Belongs to the synaptotagmin family.
    Contains 2 C2 domains.
  • ドメイン
    The first C2 domain mediates Ca(2+)-dependent phospholipid binding.
    The second C2 domain mediates interaction with SV2A and STN2.
  • 細胞内局在
    Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cytoplasmic vesicle > secretory vesicle > chromaffin granule membrane. Cytoplasm. Synaptic vesicles and chromaffin granules.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp781D2042 antibody
    • FLJ42519 antibody
    • p65 antibody
    • SVP65 antibody
    • Synaptotagmin 2 antibody
    • Synaptotagmin I antibody
    • Synaptotagmin II antibody
    • Synaptotagmin-1 antibody
    • SYT antibody
    • Syt1 antibody
    • SYT1_HUMAN antibody
    • Syt2 antibody
    • SytI antibody
    see all

画像

  • All lanes : Anti-Synaptotagmin 1 antibody (ab82414) at 1/1000 dilution

    Lane 1 : Rat Brain lysate
    Lane 2 : Mouse Brain lysate
    Lane 3 : Xenopus Ovary lysate

    Developed using the ECL technique

    Predicted band size : 48 kDa
    Observed band size : 65 kDa (why is the actual band size different from the predicted?)

プロトコール

参考文献

ab82414 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab82414.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録