Anti-Synaptotagmin 1 抗体 (ab82414)

製品の概要

• 製品名
  Anti-Synaptotagmin 1 antibody
  Synaptotagmin 1 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to Synaptotagmin 1
• アプリケーション
  適用あり: WBmore details
• 種交差性
  交差種: Rat, Xenopus laevis
  非交差種: Mouse
• 免疫原

  Synthetic peptide derived from sequence near the amino terminus of rat Synaptotagmin 1, conjugated to KLH

• ポジティブ･コントロール
  • Rat Brain and Xenopus Ovary lysates.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• バッファー
  Preservative: 0.09% Sodium Azide
  Constituents: 50% Glycerol, PBS, pH 7.2
• Concentration information loading...
• 精製度
  Protein A purified
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Neuroscience
  • Neurotransmission
  • Secretory Vesicles
  • Regulation

  • Neuroscience
  • Neurotransmission
  • Secretory Vesicles
  • Other

  • Signal Transduction
  • Protein Trafficking
  • Vesicle Transport
  • Regulation

  • Neuroscience
  • Cell Type Marker
  • Neuron marker
  • Synapse marker

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能
  May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
• 配列類似性
  Belongs to the synaptotagmin family.
  Contains 2 C2 domains.
• ドメイン
  The first C2 domain mediates Ca(2+)-dependent phospholipid binding.
  The second C2 domain mediates interaction with SV2A and STN2.
• 細胞内局在
  Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cytoplasmic vesicle > secretory vesicle > chromaffin granule membrane. Cytoplasm. Synaptic vesicles and chromaffin granules.

• Target information above from: UniProt accession P21579 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 25716 Rat
  • SwissProt: P21707 Rat
  • Unigene: 216272 Rat
• 別名
  • DKFZp781D2042 antibody
  • FLJ42519 antibody
  • p65 antibody

  • SVP65 antibody
  • Synaptotagmin 2 antibody
  • Synaptotagmin I antibody
  • Synaptotagmin II antibody
  • Synaptotagmin-1 antibody
  • SYT antibody
  • Syt1 antibody
  • SYT1_HUMAN antibody
  • Syt2 antibody
  • SytI antibody

  see all

プロトコール

• Western blot protocols