製品の概要

  • 製品名
    Anti-Synaptopodin antibody
    Synaptopodin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Synaptopodin
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Synthetic peptide:

    GQRSPKLSQEALQTGHPSS

    conjugated to KLH, corresponding to internal sequence amino acids 184-202 of Rat Synaptopodin

  • ポジティブ・コントロール
    • Cytosolic S1 fraction of rat brain.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 15mM Sodium Azide
    Constituents: 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 精製度
    IgG fraction
  • 特記事項(精製)
    Whole antiserum was fractionated and then further purified by ion-exchange chromatography to provide the IgG fraction of antiserum that is essentially free of other rabbit serum proteins.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab50859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報
    WB: Minimum dilution 1/3000. Predicted molecular weight: 100 kDa.
    Staining of synaptopodin in immunoblotting is specifically inhibited with the
    synaptopodin immunizing peptide (rat, amino acids 184-202).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.
    • 組織特異性
      Expressed in cerebral cortex.
    • 配列類似性
      Belongs to the synaptopodin family.
    • 翻訳後修飾
      O-glycosylated.
      Isoform 2 is phosphorylated on Ser-826, Thr-836, Ser-840 and Ser-871.
    • 細胞内局在
      Cytoplasm > cytoskeleton. Cell junction > tight junction. Perikaryon. Cell projection > dendritic spine. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Asssociated with dendritic spines of a subset of synapses.
    • Information by UniProt
    • 参照データベース
    • 別名
      • KIAA1029 antibody
      • Synaptopodin antibody
      • SYNPO antibody
      • SYNPO_HUMAN antibody

    プロトコール

    Anti-Synaptopodin antibody (ab50859) 使用論文

    This product has been referenced in:
    • Moriguchi T  et al. Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect. Mol Cell Biol 36:2272-81 (2016). IHC ; Mouse . Read more (PubMed: 27296697) »
    • Reissner KJ  et al. AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis. J Neurosci 31:5648-58 (2011). WB ; Rat . Read more (PubMed: 21490206) »

    See all 2 Publications for this product

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    There are currently no Abreviews or Questions for ab50859.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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