製品の概要

  • 製品名
    Anti-Synaptopodin antibody
    Synaptopodin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Synaptopodin
  • アプリケーション
    適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide from the C terminal region of Human Synaptopodin, conjugated to KLH.

  • ポジティブ・コントロール
    • Human perineural or perivascular process.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab117702 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 99 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能
    Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.
  • 組織特異性
    Expressed in cerebral cortex.
  • 配列類似性
    Belongs to the synaptopodin family.
  • 翻訳後修飾
    O-glycosylated.
    Isoform 2 is phosphorylated on Ser-826, Thr-836, Ser-840 and Ser-871.
  • 細胞内局在
    Cytoplasm > cytoskeleton. Cell junction > tight junction. Perikaryon. Cell projection > dendritic spine. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Asssociated with dendritic spines of a subset of synapses.
  • Information by UniProt
  • 参照データベース
  • 別名
    • KIAA1029 antibody
    • Synaptopodin antibody
    • SYNPO antibody
    • SYNPO_HUMAN antibody

画像

  • Human Perineural Processes, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117702 at 5µg/ml.
  • Human Perivascular Processes, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117702 at 5µg/ml.

参考文献

ab117702 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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