Anti-Synaptophysin 抗体 [SP17] (ab24729)

製品の概要

  • 製品名Anti-Synaptophysin antibody [SP17]
    Synaptophysin 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [SP17] to Synaptophysin
  • 特異性SP17 reacts with native, denatured and recombinant synaptic vesicle protein synaptophysin expressed in CHO cells.
  • アプリケーション適用あり: WB, ICC, ELISAmore details
  • 種交差性
    交差種: Rat, Human, Pig
  • 免疫原

    Tissue/ cell preparation of a crude synaptic preparation from the post mortem brain (Human)

  • 特記事項


    The antibody is particularly valueable for immunocytochemical studies of the brain due to its stability in formalin sections.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: Ascites
  • Concentration information loading...
  • 精製度Ascites
  • 一次抗体 備考The antibody is particularly valueable for immunocytochemical studies of the brain due to its stability in formalin sections.
  • ポリ/モノモノクローナル
  • クローン名SP17
  • アイソタイプIgM
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab24729 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 40 kDa.
ICC 1/1000.
ELISA 1/5000.

ターゲット情報

  • 機能Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
  • 組織特異性Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
  • 関連疾患Mental retardation, X-linked, SYP-related
  • 配列類似性Belongs to the synaptophysin/synaptobrevin family.
    Contains 1 MARVEL domain.
  • ドメインThe calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.
  • 翻訳後修飾Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
  • 細胞内局在Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell junction, synapse, synaptosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Major synaptic vesicle protein p38 antibody
    • MRX96 antibody
    • MRXSYP antibody
    • Syn p38 antibody
    • Synaptophysin antibody
    • Syp antibody
    • SYPH antibody
    • SYPH_HUMAN antibody
    • SypI antibody
    see all

Anti-Synaptophysin antibody [SP17] (ab24729) 使用論文

ab24729 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. Synaptophysin antibodies ab11105 and ab24729 are derived from two different monoclonal clones: [SP15] and [SP17]. They were raised against different immunogens and recognise different epitopes. Both antisera have als...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"