Anti-Synaptobrevin 抗体 [4E240] (ab18013)

製品の概要

  • 製品名Anti-Synaptobrevin antibody [4E240]
    Synaptobrevin 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4E240] to Synaptobrevin
  • 特異性Detects a ~18kD protein in WB, corresponding to predicted size of VAMP from human, mouse, rat, bovine, guinea pig, hamster, monkey, porcine, rabbit, sheep and Xenopus tissue. This antibody detects VAMP1 (amino acids 1-118) and VAMP2 (amino acids 33-96)-GST fusion proteins expressed in E. coli. No reactivity was seen with a ~18kD protein in mouse liver extracts.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Sheep, Rabbit, Guinea pig, Hamster, Cow, Human, Pig, Xenopus laevis, Monkey
  • 免疫原

    Tissue/ cell preparation (Human). Mice were immunized with synaptic vesicle containing fractions which were immunoprecipitated from human brain homogenates using anti-human synaptophysin monoclonal antibodies.

  • ポジティブ・コントロール
    • Rat brain.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab18013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 13 kDa.

ターゲット情報

  • 関連性Synaptobrevins are highly conserved between vertebrates and invertebrates. It is a major constituent of synaptic vesicles and peptidergic secretory granules in all neurons examined so far. In addition, it is present on secretory granules of neuroendocrine cells. Synaptobrevins, Syntaxins, and the 25 kDa synaptosomal associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane.
  • 細胞内局在Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane. Single-pass type IV membrane protein. Cell junction > synapse > synaptosome. Isoform 3 is found in mitochondria, mitochondrial outer membrane.
  • 参照データベース
  • 別名
    • SYB antibody
    • SYB1 antibody
    • Synaptobrevin 1 antibody
    • VAMP antibody
    • VAMP1 antibody
    • Vesicle associated membrane protein 1 antibody
    see all

Anti-Synaptobrevin antibody [4E240] (ab18013) 使用論文

ab18013 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"