Anti-Synapsin I (phospho S9) 抗体 (ab47767)

製品の概要

  • 製品名Anti-Synapsin I (phospho S9) antibody
    Synapsin I 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Synapsin I (phospho S9)
  • 特異性This antibody detects synapsin only when phosphorylated at serine 9. The antibody is expected to recognize phosphorylated serine 9 of all synapsin I isoforms.
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthesized phosphopeptide derived from human synapsin I around the phosphorylation site of serine 9 (R-L-SP-D-S)

  • ポジティブ・コントロール
    • 293 cell extract.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab47767 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/20000.
WB 1/500 - 1/1000. Detects a band of approximately 74 kDa (predicted molecular weight: 74 kDa).

ターゲット情報

  • 機能Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
  • 関連疾患Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders [MIM:300491]. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
  • 配列類似性Belongs to the synapsin family.
  • 翻訳後修飾Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cell junction > synapse. Golgi apparatus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Brain protein 4.1 antibody
    • SYN 1 antibody
    • SYN 1a antibody
    • SYN 1b antibody
    • SYN I antibody
    • SYN1 antibody
    • SYN1_HUMAN antibody
    • SYN1a antibody
    • SYN1b antibody
    • Synapsin 1 antibody
    • Synapsin I antibody
    • Synapsin-1 antibody
    • Synapsin1 antibody
    • SynapsinI antibody
    • SYNI antibody
    see all

Anti-Synapsin I (phospho S9) antibody 画像

  • All lanes : Anti-Synapsin I (phospho S9) antibody (ab47767) at 1/500 dilution

    Lane 1 : 293 cell extract treated with PMA (200nM, 30min)
    Lane 2 : 293 cell extract


    Predicted band size : 74 kDa
    Observed band size : 74 kDa

Anti-Synapsin I (phospho S9) antibody (ab47767) 使用論文

ab47767 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab47767.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"