製品の概要

  • 製品名Anti-Synapsin I antibody
    Synapsin I 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Synapsin I
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Mouse, Rat, Cow, Human
    交差が予測される動物種: Dog, Pig
  • 免疫原

    Synthetic peptide:

    GGQQRQGPPQKPPGPAGP

    conjugated to KLH, corresponding to amino acids 583-600 of Human Synapsin I (GenBank accession number: M58378).

  • ポジティブ・コントロール
    • Rar brain tissue extract

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 75mM Sodium chloride, 5mM EDTA, 25mM Sodium borate, 100mM Boric Acid, pH 8.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)This antibody was purified on a peptide bound immunoaffinity column.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab90501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.05 µg/ml. Predicted molecular weight: 74 kDa.
IP Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
  • 関連疾患Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders [MIM:300491]. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
  • 配列類似性Belongs to the synapsin family.
  • 翻訳後修飾Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cell junction > synapse. Golgi apparatus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Brain protein 4.1 antibody
    • SYN 1 antibody
    • SYN 1a antibody
    • SYN 1b antibody
    • SYN I antibody
    • SYN1 antibody
    • SYN1_HUMAN antibody
    • SYN1a antibody
    • SYN1b antibody
    • Synapsin 1 antibody
    • Synapsin I antibody
    • Synapsin-1 antibody
    • Synapsin1 antibody
    • SynapsinI antibody
    • SYNI antibody
    see all

Anti-Synapsin I antibody (ab90501) 使用論文

ab90501 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab90501.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"