製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to SV2A
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Rat
    交差が予測される動物種: Mouse, Horse, Cow, Dog, Human, Pig, Chimpanzee, Zebrafish, Rhesus monkey
  • 免疫原

    Synthetic peptide:

    C-TVELYPSDKRTTA

    , corresponding to internal sequence amino acids 673-685 of Human SV2A (NP_055664.2)

  • ポジティブ・コントロール
    • Rat brain lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab77177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報
    Peptide ELISA: antibody detection limit dilution 1/64000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 83 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.
    • 配列類似性
      Belongs to the major facilitator superfamily.
    • 翻訳後修飾
      Phosphorylation by CK1 of the N-terminal cytoplasmic domain regulates interaction with SYT1.
      N-glycosylated.
    • 細胞内局在
      Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Enriched in chromaffin granules, not present in adrenal microsomes. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.
    • Information by UniProt
    • 参照データベース
    • 別名
      • KIAA0736 antibody
      • OTTHUMP00000014065 antibody
      • SV2 antibody
      • Sv2a antibody
      • SV2A_HUMAN antibody
      • Synaptic vesicle glycoprotein 2 antibody
      • Synaptic vesicle glycoprotein 2A antibody
      • Synaptic vesicle protein 2a antibody
      see all

    画像

    • Anti-SV2A antibody (ab77177) at 0.3 µg/ml + rat brain lysate in RIPA buffer at 35 µg

      Predicted band size : 83 kDa
      Observed band size : 80 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 28 kDa. We are unsure as to the identity of these extra bands.

    プロトコール

    参考文献

    ab77177 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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