製品の概要

  • 製品名
    Anti-Su(var)3-9 antibody
  • 製品の詳細
    Rabbit polyclonal to Su(var)3-9
  • 特異性
    ab4811 will recognise KMT1 / Clr4 / Su(var)3-9 but not eIF2-gamma due to immunogen selection.
  • アプリケーション
    適用あり: ICC/IFmore details
  • 種交差性

    交差が予測される動物種: Drosophila melanogaster
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 150 - 250 of Fruit fly (Drosophila melanogaster) KMT1/ Clr4/ Su(var)3-9.

    (Peptide available as ab87896.)

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab4811 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/100.

ターゲット情報

  • 関連性
    Histone-lysine N-methyltransferase, H3 lysine-9 specific. Major histone methyltransferase. Methylates Lys-9 of histone H3. H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting Su(var)205/HP1 to methylated histones. Seems to be involved in heterochromatic gene silencing including the modification of position-effect-variegation. There are three isoforms, isoform A and isoform B share the first 80 amino acid residues. Experimental confirmation may be lacking for some isoforms.
  • 細胞内局在
    Nuclear
  • 参照データベース
    • 別名
      • H3-K9-HMTase antibody
      • Histone H3-K9 methyltransferase antibody
      • Su(var)3-9 antibody
      • Suppressor of variegation protein 3-9 antibody
      • suv39 antibody
      see all

    参考文献

    This product has been referenced in:
    • Huang XA  et al. A major epigenetic programming mechanism guided by piRNAs. Dev Cell 24:502-16 (2013). Read more (PubMed: 23434410) »
    • Krstic D  et al. Regulated proteolytic processing of Reelin through interplay of tissue plasminogen activator (tPA), ADAMTS-4, ADAMTS-5, and their modulators. PLoS One 7:e47793 (2012). Read more (PubMed: 23082219) »

    See all 2 Publications for this product

    レビューと Q&A

    Application
    Immunocytochemistry/ Immunofluorescence
    Sample
    Stylonychia lemnae Cell (single cell organism)
    Specification
    single cell organism
    Fixative
    Paraformaldehyde
    Permeabilization
    Yes - 0.5%TritonX100/PBS, brief 0.1N HCl treatment, brief pepsin treatment
    Blocking step
    BSA as blocking agent for 30 minute(s) · Concentration: 4% · Temperature: 20°C
    Username

    Abcam user community

    Verified customer

    投稿 Jul 20 2007

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    登録