Anti-Surfactant protein D 抗体 [10B2] (ab26267)

製品の概要

• 製品名
  Anti-Surfactant protein D antibody [10B2]
  Surfactant protein D 一次抗体 製品一覧
• 製品の詳細
  Mouse monoclonal [10B2] to Surfactant protein D
• 特異性
  This antibody is specific for Surfactant protein D from amniotic fluid, serum and bronchioalveolar lavage. In Western Blotting this antibody reacts with non-reduced Surfactant protein D only.
• アプリケーション
  適用あり: ELISA, WBmore details
• 種交差性
  交差種: Human
  
• 免疫原

  Full length native protein (purified) (Human) - Surfactant protein D purified from late pregnancy amniotic fluid.

• エピトープ
  The epitope this antibody reacts with is localised within the c-terminal neck (CRD) of Surfactant protein D.
• 特記事項

  
  

  This antibody does not influence Surfactant protein D's binding to carbohydrates.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• バッファー
  Preservative: 15mM Sodium Azide
  Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
• Concentration information loading...
• 精製度
  Protein A purified
• 一次抗体 備考
  This antibody does not influence Surfactant protein D's binding to carbohydrates.
• ポリ/モノ
  モノクローナル
• クローン名
  10B2
• ミエローマ
  x63-Ag8.653
• アイソタイプ
  IgG2a
• 軽鎖の種類
  kappa
• 研究分野
  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

  • Microbiology
  • Protein
  • Human Protein
  • Defensin

  • Signal Transduction
  • Signaling Pathway
  • Calcium Signaling
  • Calcium Binding Proteins

  • Cell Biology
  • Other Antibodies
  • Oxidative Stress

  • Cancer
  • Cancer Metabolism
  • Cellular metabolic process

  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Oxidative stress

  • Metabolism
  • Types of disease
  • Cancer

関連製品

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

アプリケーション

ターゲット情報

• 機能
  Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
• 配列類似性
  Belongs to the SFTPD family.
  Contains 1 C-type lectin domain.
  Contains 1 collagen-like domain.
• 翻訳後修飾
  The N-terminus is blocked.
  Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.
• 細胞内局在
  Secreted > extracellular space > extracellular matrix. Secreted > extracellular space > surface film.

• Target information above from: UniProt accession P35247 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 6441 Human
  • Omim: 178635 Human
  • SwissProt: P35247 Human
  • Unigene: 253495 Human
• 別名
  • COLEC 7 antibody
  • COLEC7 antibody
  • Collectin-7 antibody

  • Collectin7 antibody
  • Lung surfactant protein D antibody
  • PSP D antibody
  • PSP-D antibody
  • PSP-D Surfactant protein D antibody
  • PSPD antibody
  • Pulmonary surfactant apoprotein antibody
  • Pulmonary surfactant associated protein D antibody
  • Pulmonary surfactant associated protein PSP-D antibody
  • Pulmonary surfactant-associated protein D antibody
  • SFTP 4 antibody
  • SFTP4 antibody
  • SFTPD antibody
  • SFTPD_HUMAN antibody
  • SP D antibody
  • SP-D antibody
  • Surfactant associated protein pulmonary 4 antibody
  • Surfactant pulmonary associated protein D antibody

  see all

プロトコール

• Western blot protocols