製品の概要

  • 製品名Anti-SUN1 antibody
    SUN1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to SUN1
  • 特異性This antibody is reactive against mammalian transfected lysate.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    SUN1 (AAH13613, 1 a.a. ~ 258 a.a) full-length human protein.

  • ポジティブ・コントロール
    • SUN1 transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab67999 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 35 kDa (predicted molecular weight: 90 kDa).

ターゲット情報

  • 機能Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs).
  • 配列類似性Contains 1 SUN domain.
  • ドメインThe SUN domain may play a role in the nuclear anchoring and/or migration.
  • 細胞内局在Nucleus inner membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Protein unc-84 homolog A antibody
    • Sad1 and UNC84 domain containing 1 antibody
    • Sad1/unc 84 protein like 1 antibody
    • Sad1/unc-84 protein-like 1 antibody
    • Sun domain-containing protein 1 antibody
    • Sun1 antibody
    • SUN1_HUMAN antibody
    • UNC 84 homolog A (C elegans) antibody
    • UNC 84A antibody
    • UNC84 A antibody
    • UNC84 antibody
    • UNC84 homolog A (C elegans) antibody
    • UNC84A antibody
    see all

Anti-SUN1 antibody 画像

  • All lanes : Anti-SUN1 antibody (ab67999) at 1/500 dilution

    Lane 1 : SUN1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 90 kDa
    Observed band size : 35 kDa (why is the actual band size different from the predicted?)

Anti-SUN1 antibody (ab67999) 使用論文

ab67999 has not yet been referenced specifically in any publications.

Product Wall

Abreviews
Application Western blot
Loading amount 50 µg
Gel Running Conditions Reduced Denaturing (4-12%)
Sample Human Cell lysate - whole cell (HeLa, RPE-1)
Specification HeLa, RPE-1
Blocking step Milk as blocking agent for 16 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 4°C
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投稿 Jul 09 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"