製品の概要

  • 製品名
    Sulindac sulfide
  • 製品の詳細
    Active metabolite of Sulindac. COX-1 and 2 inhibitor.
  • 生理活性の詳細
    Cell-permeable, active metabolite of Sulindac. Inhibits Ras-induced malignant transformation and Ras/Raf-dependent transactivation. COX-1 and 2 inhibitor (Ki values are 1.02 and 10.43 μM, respectively). Additionally, inhibits γ-secretase. Apoptosis inducer.
  • 精製度
    > 98%

製品の特性

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