製品の概要

  • 製品名Anti-Substance P antibody [M09205]
    Substance P 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [M09205] to Substance P
  • アプリケーション適用あり: IHC-Fr, IHC-FoFrmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Substance-P conjugated to BSA.

  • 特記事項


    Substance P belongs to the tachykinin family. These are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab7340 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr Use at an assay dependent dilution.
IHC-FoFr Use at an assay dependent concentration. PubMed: 21294877

ターゲット情報

  • 機能Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
  • 配列類似性Belongs to the tachykinin family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C-terminal-flanking peptide antibody
    • Hs.2563 antibody
    • neurokinin 1 antibody
    • neurokinin 2 antibody
    • neurokinin A antibody
    • neurokinin alpha antibody
    • Neuromedin L antibody
    • neuropeptide gamma antibody
    • neuropeptide K antibody
    • NK2 antibody
    • NKA antibody
    • NKNA antibody
    • NPK antibody
    • PPT antibody
    • preprotachykinin antibody
    • protachykinin antibody
    • protachykinin-1 antibody
    • Substance K antibody
    • SubstanceP antibody
    • TAC1 antibody
    • TAC2 antibody
    • TAC2, formerly antibody
    • Tachykinin 1 antibody
    • tachykinin 2 antibody
    • tachykinin 2, formerly antibody
    • Tachykinin precursor 1 antibody
    • tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) antibody
    • Tachykinin1 antibody
    • TKN1_HUMAN antibody
    see all

Anti-Substance P antibody [M09205] 画像

  • Immunohistochemical analysis of frozen neonatal murine DRG explants, staining Substance P with ab7340 at 1/200 dilution.

    Tissue was fixed in paraformaldehyde, cut into 10 µm sections, permeabilized with 0.1% SDS for 5 mins and incubated in 10% foetal calf serum in TBST for 10 mins. Sections were incubated with primary antibody overnight before incubating with Texas Red-conjugated goat anti-rat secondary antibody (1/250) for 40 minutes at room temperature.

Anti-Substance P antibody [M09205] (ab7340) 使用論文

This product has been referenced in:
  • George L  et al. Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons. Proc Natl Acad Sci U S A 110:18698-703 (2013). Mouse . Read more (PubMed: 24173031) »
  • Wolff G  et al. Neuronal organization of the hemiellipsoid body of the land hermit crab, Coenobita clypeatus: correspondence with the mushroom body ground pattern. J Comp Neurol 520:2824-46 (2012). Read more (PubMed: 22547177) »

See all 3 Publications for this product

Product Wall

Application Immunohistochemistry (Frozen sections)
Sample Human Tissue sections (nasal mucosa)
Specification nasal mucosa
Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 24°C
Fixative Paraformaldehyde
Username

Mr. Duc Dung Le

Verified customer

投稿 Jun 10 2016

Application Immunohistochemistry (PFA perfusion fixed frozen sections)
Blocking step Serum as blocking agent for 45 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
Antigen retrieval step None
Sample Mouse Tissue sections (Trigeminal ganglion)
Specification Trigeminal ganglion
Permeabilization No
Fixative Zamboni
Username

Mr. Duc Dung Le

Verified customer

投稿 Apr 10 2015



ab7340 is not a purified antibody, which would typically be suspended in a colorless buffer such as PBS. Rather ab7340 is an unpurified tissue culture supernatant. Tissue culture medium typically has a light purple/pinkish hue so the color yo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"