製品の概要

  • 製品名
    Anti-STRC antibody
  • 製品の詳細
    Rabbit polyclonal to STRC
  • アプリケーション
    適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    antigen sequence, corresponding to amino acids 411-541 of Human STRC.

  • ポジティブ・コントロール
    • Human bone marrow tissue; RT 4 and U 251 MG cell lysates.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab121485 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

ターゲット情報

  • 関連疾患
    Defects in STRC are the cause of deafness autosomal recessive type 16 (DFNB16) [MIM:603720]. DFNB16 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
    Defects in STRC are a cause of deafness-infertility syndrome (DIS) [MIM:611102]. DIS is characterized by deafness and infertility and is caused by large contiguous gene deletions at 15q15.3 that removes both STRC and CATSPER2 genes.
  • 配列類似性
    Belongs to the stereocilin family.
  • 細胞内局在
    Cell surface. Associated with the hair bundle.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DFNB16 antibody
    • Stereocilin antibody
    • STRC antibody
    • STRC_HUMAN antibody

Anti-STRC antibody 画像

  • ab121485, at 1/450 dilution, staining STRC in paraffin-embedded Human bone marrow tissue by Immunohistochemistry, showing strong cytoplasmic positivity in Megakaryocytes.
  • All lanes : Anti-STRC antibody (ab121485) at 1/250 dilution

    Lane 1 : RT 4 cell lysate
    Lane 2 : U 251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate

    Developed using the ECL technique

Anti-STRC antibody (ab121485) 使用論文

ab121485 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab121485.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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