製品の概要

  • 製品名Anti-Stefin B antibody
    Stefin B 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Stefin B
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Horse, Dog, Chimpanzee
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 49 - 98 (AGTNYFIKVH VGDEDFVHLR VFQSLPHENK PLTLSNYQTN KAKHDELTYF) of Human Stefin B (NP_000091).

  • ポジティブ・コントロール
    • WB: Transfected 293T cell lysate IHC-P: Human kidney tissue

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab104798 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.25 µg/ml. Predicted molecular weight: 11 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B.
  • 関連疾患Defects in CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) [MIM:254800]. EPM1 is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The onset, occurring between 6 and 13 years of age, is characterized by convulsions. Myoclonus begins 1 to 5 years later. The twitchings occur predominantly in the proximal muscles of the extremities and are bilaterally symmetrical, although asynchronous. At first small, they become late in the clinical course so violent that the victim is thrown to the floor. Mental deterioration and eventually dementia develop.
  • 配列類似性Belongs to the cystatin family.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CHROW21 antibody
    • CPI B antibody
    • CPI-B antibody
    • CST 6 antibody
    • CST6 antibody
    • CSTB antibody
    • Cystatin B (stefin B) antibody
    • Cystatin B antibody
    • Cystatin-B antibody
    • CYTB antibody
    • CYTB_HUMAN antibody
    • EPM1 antibody
    • EPM1A antibody
    • Liver thiol proteinase inhibitor antibody
    • PME antibody
    • Stefin-B antibody
    • STF B antibody
    • STFB antibody
    • ULD antibody
    see all

Anti-Stefin B antibody 画像

  • Anti-Stefin B antibody (ab104798) at 0.25 µg/ml + Transfected 293T cell lysate at 10 µg

    Predicted band size : 11 kDa
    Gel concentration: 15%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis human kidney tissue labelling Sefin B with ab104798 at 4-8µg/ml. Arrows indicate positively labelled epithelial cells of the renal tubule. Magnification: 400X.

Anti-Stefin B antibody (ab104798) 使用論文

ab104798 has not yet been referenced specifically in any publications.

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