製品の概要

  • 製品名Anti-Stefin B antibody [2F1]
    Stefin B 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2F1] to Stefin B
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant human Stefin B (1-98 aa) purified from E. coli

  • ポジティブ・コントロール
    • A549 cell lysate
  • 特記事項


    is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Stefin B protein.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)ab72353 was purified from mouse ascitic fluids by protein G affinity chromatography.
  • 一次抗体 備考is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Stefin B protein.
  • ポリ/モノモノクローナル
  • クローン名2F1
  • アイソタイプIgG2b
  • 軽鎖の種類kappa
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab72353 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/3000. Detects a band of approximately 14 kDa (predicted molecular weight: 11 kDa).
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B.
  • 関連疾患Defects in CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) [MIM:254800]. EPM1 is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The onset, occurring between 6 and 13 years of age, is characterized by convulsions. Myoclonus begins 1 to 5 years later. The twitchings occur predominantly in the proximal muscles of the extremities and are bilaterally symmetrical, although asynchronous. At first small, they become late in the clinical course so violent that the victim is thrown to the floor. Mental deterioration and eventually dementia develop.
  • 配列類似性Belongs to the cystatin family.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CHROW21 antibody
    • CPI B antibody
    • CPI-B antibody
    • CST 6 antibody
    • CST6 antibody
    • CSTB antibody
    • Cystatin B (stefin B) antibody
    • Cystatin B antibody
    • Cystatin-B antibody
    • CYTB antibody
    • CYTB_HUMAN antibody
    • EPM1 antibody
    • EPM1A antibody
    • Liver thiol proteinase inhibitor antibody
    • PME antibody
    • Stefin-B antibody
    • STF B antibody
    • STFB antibody
    • ULD antibody
    see all

Anti-Stefin B antibody [2F1] 画像

  • Anti-Stefin B antibody [2F1] (ab72353) at 1/1000 dilution + A549 cells lysate at 35 µg

    Secondary
    goat anti-mouse secondary antibody conjugated to HRP
    Developed using the ECL technique

    Predicted band size : 11 kDa
    Observed band size : 14 kDa (why is the actual band size different from the predicted?)

Anti-Stefin B antibody [2F1] (ab72353) 使用論文

This product has been referenced in:
  • Burgener A  et al. A systems biology examination of the human female genital tract shows compartmentalization of immune factor expression. J Virol 87:5141-50 (2013). Human . Read more (PubMed: 23449785) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"