製品の概要

  • 製品名
    Stauprimide
  • 製品の詳細
    Stem cell differentiation primer. Staurosporine analog.
  • 生理活性の詳細
    Primes embryonic stem cells (ESCs) for efficient differentiation. Potently increases Sox17+/Sox7- cell differentiation from ESCs (EC50 = 0.3 μM). Downregulates c-Myc expression by inhibiting nucleoside diphosphate kinase B (NME2) nuclear localization. Staurosporine (ab120056) analog.
  • 精製度
    > 99%

製品の特性

  • 体系名
    N-[(9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1,3-dioxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]-benzodiazonin-11-yl]-N-methylbenzamide
  • 分子量
    584.63
  • 構造式
    Chemical Structure
  • 分子式
    C35H28N4O5
  • CAS 番号
    154589-96-5
  • PubChem 登録番号
    46245328
  • 保存方法
    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • 溶解性
    Soluble in DMSO to 100 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES 線形表記
    O=C(c1ccccc1)N(C)[C@@H]2C[C@H]9O[C@@](C)([C@@H]2OC)n5c4c3n9c8ccccc8c3c7c(c4c6ccccc56)C(=O)NC7=O
  • 由来

    Synthetic

  • 研究分野

参考文献

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