製品の概要

製品の詳細

  • 由来
    Synthetic

特性

Our Abpromise guarantee covers the use of ab110446 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Sodium azide
    Constituent: 0.1% BSA

関連情報

  • 別名
    • Double stranded RNA binding protein Staufen homolog
    • Double stranded RNA binding protein Staufen homolog 1
    • Double-stranded RNA-binding protein Staufen homolog 1
    • FLJ25010
    • MGC124588
    • PPP1R150
    • STAU
    • STAU1
    • STAU1_HUMAN
    • staufen
    • Staufen RNA binding protein (Drosophila)
    • Staufen RNA binding protein homolog 1
    • Staufen, Drosophila, homolog of, 1
    • Staufen, RNA binding protein, homolog 1 (Drosophila)
    • staufen-like
    see all
  • 機能
    Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
  • 組織特異性
    Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.
  • 配列類似性
    Contains 3 DRBM (double-stranded RNA-binding) domains.
  • ドメイン
    One of the DRDB could be involved in RER binding.
    The C-terminal contains the tubulin binding domain (TBD).
  • 細胞内局在
    Cytoplasm. Rough endoplasmic reticulum. Localizes exclusively with the rough reticulum endoplasmic.
  • Information by UniProt

参考文献

ab110446 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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