製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to STAT5a
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Three synthetic peptides (Human) conjugated to KLH

  • ポジティブ・コントロール
    • An induced culture of E. coli

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab86030 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報
    WB: 1/1000. Detects a band of approximately 105 kDa (predicted molecular weight: 91 kDa). Tag is 14kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
    • 配列類似性
      Belongs to the transcription factor STAT family.
      Contains 1 SH2 domain.
    • 翻訳後修飾
      Tyrosine phosphorylated in response to IL-2, IL-3, IL-7, IL-15, GM-CSF, growth hormone, prolactin, erythropoietin and thrombopoietin. Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for maximal transcriptional activity.
    • 細胞内局在
      Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Mammary gland factor antibody
      • MGF antibody
      • Signal transducer and activator of transcription 5A antibody
      • STA5A_HUMAN antibody
      • STAT 5 antibody
      • STAT 5A antibody
      • STAT5 antibody
      • STAT5A antibody
      see all

    画像

    • All lanes : Anti-STAT5a antibody (ab86030) at 1/1000 dilution

      Lane 1 : An un-induced culture of E. coli
      Lane 2 : An induced culture of E. coli

      Lysates/proteins at 1/5000 dilution per lane.

      Secondary
      Anti-Rabbit IgG HRP at 1/1000 dilution

      Predicted band size : 91 kDa
      Observed band size : 49,75,105 kDa (why is the actual band size different from the predicted?)


      Exposure time : 60 minutes

    プロトコール

    参考文献

    ab86030 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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