製品の概要

  • 製品名Anti-STAT5a antibody
    STAT5a 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to STAT5a
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide:

    CRLSPPAGLFTSARGSLS

    conjugated to KLH, corresponding to amino acids 778-794 of Human STAT5a.

  • ポジティブ・コントロール
    • Mouse 3T3 cell lysate.
  • 特記事項If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab12195 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 95 kDa.
IP Use at 4 µg/mg of lysate.

ターゲット情報

  • 機能Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
  • 配列類似性Belongs to the transcription factor STAT family.
    Contains 1 SH2 domain.
  • 翻訳後修飾Tyrosine phosphorylated in response to IL-2, IL-3, IL-7, IL-15, GM-CSF, growth hormone, prolactin, erythropoietin and thrombopoietin. Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for maximal transcriptional activity.
  • 細胞内局在Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Mammary gland factor antibody
    • MGF antibody
    • Signal transducer and activator of transcription 5A antibody
    • STA5A_HUMAN antibody
    • STAT 5 antibody
    • STAT 5A antibody
    • STAT5 antibody
    • STAT5A antibody
    see all

Anti-STAT5a antibody (ab12195) 使用論文

This product has been referenced in:
  • Elliott S  et al. Lack of expression and function of erythropoietin receptors in the kidney. Nephrol Dial Transplant : (2011). IP ; Human . Read more (PubMed: 22167585) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"