製品の概要

  • 製品名Anti-STAT4 (phospho Y693) antibody
    STAT4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to STAT4 (phospho Y693)
  • アプリケーション適用あり: WB, IHC-P, ELISA, IPmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    The antiserum was produced against synthesized phosphopeptide derived from human STAT4 around the phosphorylation site of Tyrosine 693.

  • ポジティブ・コントロール
    • IHC: Breast Carcinoma. WB: HeLa cells treated with IL4.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab28815 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 85 kDa.
IHC-P 1/50 - 1/100.
ELISA 1/1000 - 1/4000.
IP Use at an assay dependent concentration.

ターゲット情報

  • 機能Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.
  • 関連疾患Systemic lupus erythematosus 11
    Rheumatoid arthritis
  • 配列類似性Belongs to the transcription factor STAT family.
    Contains 1 SH2 domain.
  • 翻訳後修飾Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity.
  • 細胞内局在Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Signal transducer and activator of transcription 4 antibody
    • SLEB11 antibody
    • STAT4 antibody
    • STAT4_HUMAN antibody

Anti-STAT4 (phospho Y693) antibody 画像

  • ab28815, staining human STAT4 in breast carcinoma by immunohistochemistry, paraffin embedded tissue. left: Using STAT4 antibody (ab28815); right: The same antibody preincubated with synthesized phosphopeptide.
  • All lanes : Anti-STAT4 (phospho Y693) antibody (ab28815)

    Lane 1 : HeLa cell lysate (cells treated with IL4)
    Lane 2 : HeLa cell lysate (untreated)


    Predicted band size : 85 kDa

Anti-STAT4 (phospho Y693) antibody (ab28815) 使用論文

This product has been referenced in:
  • Cichocki F  et al. Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency. J Exp Med 211:1079-91 (2014). Read more (PubMed: 24842371) »
  • Surls J  et al. Increased Membrane Cholesterol in Lymphocytes Diverts T-Cells toward an Inflammatory Response. PLoS One 7:e38733 (2012). WB ; Mouse . Read more (PubMed: 22723880) »

See all 2 Publications for this product

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The WB image was obtained under the following conditions:

The gel was 8% SDS-PAGE. About 30 ug total protein was loaded on each lane.

As for mouse data, I found out that they have not yet been...

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