製品の概要

  • 製品名Anti-STAT2 antibody [Y141]
    STAT2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [Y141] to STAT2
  • 特異性This antibody detects both long and short forms of STAT2.
  • アプリケーション適用あり: WB, ICC, IHC-Pmore details
    適用なし: Flow Cyt or IP
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to residues near N-terminus of human Stat-2.

  • ポジティブ・コントロール
    • K562 cell lysate and human thyroid cancer
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab32367 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/5000 - 1/10000. Detects a band of approximately 98 kDa (predicted molecular weight: 98 kDa).
ICC 1/50 - 1/100.
IHC-P 1/100 - 1/250.
  • 追加情報Is unsuitable for Flow Cyt or IP.
  • ターゲット情報

    • 機能Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
    • 配列類似性Belongs to the transcription factor STAT family.
      Contains 1 SH2 domain.
    • 翻訳後修飾Tyrosine phosphorylated in response to IFN-alpha.
    • 細胞内局在Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Homo sapiens interferon alpha induced transcriptional activator antibody
      • interferon alpha induced transcriptional activator antibody
      • ISGF 3 antibody
      • ISGF3 antibody
      • MGC59816 antibody
      • P113 antibody
      • signal transducer and activator of transcription 2 113kD antibody
      • Signal transducer and activator of transcription 2 antibody
      • STAT113 antibody
      • Stat2 antibody
      • STAT2_HUMAN antibody
      see all

    Anti-STAT2 antibody [Y141] 画像

    • Anti-STAT2 antibody [Y141] (ab32367) at 1/500 dilution + K562 cell lysate

      Predicted band size : 98 kDa
      Observed band size : 100 kDa (why is the actual band size different from the predicted?)
    • Immunohistochemical analysis of paraffin-embedded human thyroid cancer using ab32367

    Anti-STAT2 antibody [Y141] (ab32367) 使用論文

    ab32367 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab32367.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"